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7/14/2026 5:50:22 AM | Browse: 1 | Download: 0
Publication Name World Journal of Orthopedics
Manuscript ID 121157
Country Spain
Received
2026-03-18 06:55
Peer-Review Started
2026-03-18 06:58
First Decision by Editorial Office Director
2026-04-04 02:50
Return for Revision
2026-04-04 02:50
Revised
2026-04-09 13:22
Publication Fee Transferred
2026-04-24 11:12
Second Decision by Editor
2026-06-08 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-08 05:30
Articles in Press
2026-06-08 05:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-07 14:22
Publish the Manuscript Online
2026-07-14 05:50
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Basic Study
Article Title Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis
Manuscript Source Unsolicited Manuscript
All Author List Luis Palacios-Díaz, Blanca Diez Sánchez, Ángel González-García, Eva Manuela Pena-Burgos, José Juan Pozo-Kreilinger, MT Carrascal-Morillo, Alejandro Bustos, Pablo Sanchez-Urgelles, Samuel Antuña and Raul Barco
ORCID
Author(s) ORCID Number
Luis Palacios-Díaz http://orcid.org/0009-0006-5691-7346
Blanca Diez Sánchez http://orcid.org/0000-0001-6524-6296
Eva Manuela Pena-Burgos http://orcid.org/0000-0001-7113-045X
José Juan Pozo-Kreilinger http://orcid.org/0000-0001-5895-4112
MT Carrascal-Morillo http://orcid.org/0000-0002-2807-9182
Alejandro Bustos http://orcid.org/0000-0001-7513-6058
Pablo Sanchez-Urgelles http://orcid.org/0009-0004-0476-2317
Samuel Antuña http://orcid.org/0000-0003-0195-305X
Raul Barco http://orcid.org/0000-0002-2182-4469
Funding Agency and Grant Number
Funding Agency Grant Number
SECEC 17th Basic Research Grant
SECOT Ayudas a Investigación en COT 2024
Corresponding Author Luis Palacios-Díaz, Department of Shoulder and Elbow Surgery, La Paz University Hospital, Paseo de la castellana 291, Madrid 28046, Spain. lpalaciosdiaz96@gmail.com
Key Words Post-traumatic arthrofibrosis; Joint stiffness; Celecoxib; Posterior capsular fibrosis; Rat model
Core Tip Post-traumatic arthrofibrosis remains a challenging condition with limited preventive strategies. In this rat model, celecoxib reduced capsular fibrosis and improved biomechanical outcomes, suggesting a potential disease-modifying effect on fibrotic remodeling rather than solely providing symptomatic relief. These findings support further investigation of celecoxib as a preventive intervention for post-traumatic joint contracture and provide a rationale for future translational and clinical studies.
Publish Date 2026-07-14 05:50
Citation

Palacios-Díaz L, Diez Sánchez B, González-García Á, Pena-Burgos EM, Pozo-Kreilinger JJ, Carrascal-Morillo M, Bustos A, Sanchez-Urgelles P, Antuña S, Barco R. Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis. World J Orthop 2026; 17(7): 121157

URL https://www.wjgnet.com/2218-5836/full/v17/i7/121157.htm
DOI https://doi.org/10.5312/wjo.121157
Full Article (PDF) WJO-17-121157-with-cover.pdf
The ARRIVE Guidelines 121157-The-ARRIVE-Guidelines.pdf
Manuscript File 121157_Auto_Edited_055456.docx
Answering Reviewers 121157-answering-reviewers.pdf
Audio Core Tip 121157-audio.m4a
Biostatistics Review Certificate 121157-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121157-conflict-of-interest-statement.pdf
Copyright License Agreement 121157-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 121157-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 121157-non-native-speakers.pdf
Supplementary Material 121157-supplementary-material.pdf
Peer-review Report 121157-peer-reviews.pdf
Scientific Misconduct Check 121157-scientific-misconduct-check.png
Scientific Editor Work List 121157-scientific-editor-work-list.pdf
CrossCheck Report 121157-crosscheck-report.pdf