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6/16/2026 8:10:07 AM | Browse: 0 | Download: 0
Publication Name World Journal of Experimental Medicine
Manuscript ID 121192
Country Greece
Received
2026-03-18 05:19
Peer-Review Started
2026-03-18 05:23
First Decision by Editorial Office Director
2026-03-27 10:47
Return for Revision
2026-03-27 10:47
Revised
2026-03-31 10:40
Publication Fee Transferred
Second Decision by Editor
2026-04-14 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-14 06:36
Articles in Press
2026-04-14 06:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-08 00:31
Publish the Manuscript Online
2026-06-16 08:10
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Correspondence
Article Title Letter to the Editor: Endocrine determinants of diabetic ketoacidosis outcomes in type 2 diabetes and insights into Gymnema sylvestre actions
Manuscript Source Unsolicited Manuscript
All Author List Charalampos Milionis, Emmanouil Zoumakis and Ioannis Ilias
ORCID
Author(s) ORCID Number
Charalampos Milionis http://orcid.org/0000-0003-2442-3772
Ioannis Ilias http://orcid.org/0000-0001-5718-7441
Funding Agency and Grant Number
Corresponding Author Ioannis Ilias, Director, MD, PhD, Department of Endocrinology, Hippocration General Hospital, No. 63 Evrou Street, Athens 11527, Greece. iiliasmd@yahoo.com
Key Words Diabetic ketoacidosis; Type 2 diabetes mellitus; Incretin axis; Glucagon-like peptide-1; Beta-cell function; Gymnema sylvestre
Core Tip Endocrine parameters - including beta-cell reserve, incretin signaling, and glucagon dynamics - are critical but underexplored determinants of diabetic ketoacidosis (DKA) outcomes in type 2 diabetes mellitus. The concurrent occurrence of acute pancreatitis in DKA, which may affect at least 15% of cases and substantially worsens prognosis, adds diagnostic complexity by masking hallmark features of both conditions and amplifying metabolic and hormonal dysregulation. The metabolic effects of Gymnema sylvestre also require deeper hormonal characterization to clarify its mechanism of action.
Publish Date 2026-06-16 08:10
Citation

Milionis C, Zoumakis E, Ilias I. Letter to the Editor: Endocrine determinants of diabetic ketoacidosis outcomes in type 2 diabetes and insights into Gymnema sylvestre actions. World J Exp Med 2026; 16(2): 121192

URL https://www.wjgnet.com/2220-315x/full/v16/i2/121192.htm
DOI https://doi.org/10.5493/wjem.v16.i2.121192
Full Article (PDF) WJEM-16-121192-with-cover.pdf
Manuscript File 121192_Auto_Edited-YJP.docx
Answering Reviewers 121192-answering-reviewers.pdf
Audio Core Tip 121192-audio.mp3
Conflict-of-Interest Disclosure Form 121192-conflict-of-interest-statement.pdf
Copyright License Agreement 121192-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 121192-non-native-speakers.pdf
Peer-review Report 121192-peer-reviews.pdf
Scientific Misconduct Check 121192-scientific-misconduct-check.png
Scientific Editor Work List 121192-scientific-editor-work-list.pdf
CrossCheck Report 121192-crosscheck-report.pdf