Publication Name	World Journal of Gastroenterology
Manuscript ID	12123
Country	Taiwan

Received	2014-06-23 08:15
Peer-Review Started	2014-06-23 11:22
To Make the First Decision	2014-08-06 17:22
Return for Revision	2014-08-08 14:15
Revised	2014-10-08 06:07
Second Decision	2014-11-10 16:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-11-19 09:18
Articles in Press	2014-11-19 09:43
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-12-16 14:15
Typeset the Manuscript	2015-02-04 10:24
Publish the Manuscript Online	2015-02-11 16:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Basic Study
Article Title	Impact of high glucose on metastasis of colon cancer cells
Manuscript Source	Unsolicited Manuscript
All Author List	Cheng-Yao Lin, Chih-Hui Lee, Chien-Cheng Huang, Song-Tay Lee, How-Ran Guo and Shih-Bin Su
Funding Agency and Grant Number	Funding Agency Grant Number Chi-Mei Medical Center Grant CMFHR10252
Corresponding Author	Shih-Bin Su, MD, PhD, Department of Occupational Medicine, Chi-Mei Medical Center, 901 Zhonghua Road, Yung-Kang District, Tainan 710, Taiwan. 880601@mail.chimei.org.tw
Key Words	Colorectal cancer; Glucose; Signal transducer and activator of transcription 3; Matrix metalloproteinase-9; Metastasis
Core Tip	It has been known from several epidemiological reports that colorectal cancer patients with comorbid diabetes have poor outcomes. The high glucose status in diabetes patients may play an important role in this process, but the possible mechanism is unclear. Our study reveals that glucose can promote colorectal cell migration and invasion, and the signal transducer and activator of transcription 3 induced matrix metalloproteinase-9 expression is involved in this process.
Publish Date	2015-02-11 16:38
Citation	Lin CY, Lee CH, Huang CC, Lee ST, Guo HR, Su SB. Impact of high glucose on metastasis of colon cancer cells. World J Gastroenterol 2015; 21(7): 2047-2057
URL	http://www.wjgnet.com/1007-9327/full/v21/i7/2047.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i7.2047

Full Article (PDF)	WJG-21-2047.pdf
Full Article (Word)	WJG-21-2047.doc
Manuscript File	12123-Review.doc
Answering Reviewers	12123-Answering reviewers.pdf
Copyright License Agreement	12123-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140623061150.pdf
Non-Native Speakers of English Editing Certificate	12123-Language certificate.pdf
Peer-review Report	12123-Peer review(s).pdf
Scientific Misconduct Check	12123-CrossCheck.jpg
Scientific Editor Work List	12123-Scientific editor work list.pdf