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9/9/2026 9:45:14 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 121235
Country China
Received
2026-03-21 06:09
Peer-Review Started
2026-03-21 11:37
First Decision by Editorial Office Director
2026-04-04 02:07
Return for Revision
2026-04-04 02:07
Revised
2026-04-28 14:52
Publication Fee Transferred
2026-05-13 08:42
Second Decision by Editor
2026-06-15 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-15 06:53
Articles in Press
2026-06-15 06:53
Edit the Manuscript by Language Editor
2026-06-25 22:51
Typeset the Manuscript
2026-08-24 00:21
Publish the Manuscript Online
2026-09-09 09:45
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Risk factors for recurrence and metastasis of stage IIIC colorectal cancer: A two-center retrospective cohort study
Manuscript Source Unsolicited Manuscript
All Author List Zheng Ruan, Ling-Xin Zhu, Yuan-Yuan Zeng, Chuan-Hui Lu, Guo-Xian Guan, Jun-Wei Wu and Fan Li
ORCID
Author(s) ORCID Number
Zheng Ruan http://orcid.org/0009-0005-3291-9366
Ling-Xin Zhu http://orcid.org/0009-0007-4681-6602
Yuan-Yuan Zeng http://orcid.org/0009-0007-7579-4916
Chuan-Hui Lu http://orcid.org/0009-0007-8307-5903
Guo-Xian Guan http://orcid.org/0000-0001-9883-3139
Jun-Wei Wu http://orcid.org/0009-0000-3405-3897
Fan Li http://orcid.org/0009-0003-7271-5830
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81970462
Key Medical and Health Project of Xiamen 3502Z20204001
Corresponding Author Fan Li, Associate Professor, MD, Department of Colorectal Surgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Zhenhai Road 55, Xiamen , China, Xiamen 361000, Fujian Province, China. lifan14521@163.com
Key Words Colorectal cancer; Stage IIIC; Recurrence and metastasis; Metastatic lymph node ratio; Prognostic factors
Core Tip Patients with stage IIIC colorectal cancer still face a high risk of recurrence and metastasis after undergoing radical surgery. This two-center retrospective study confirmed that preoperative carcinoembryonic antigen ≥ 5.0 μg/L, metastatic lymph node ratio ≥ 0.51, and positive root lymph node metastasis are independent risk factors for recurrence and metastasis. Patients possessing all three risk factors simultaneously constitute a high-risk subgroup. Identifying these key risk factors is conducive to formulating individualized surveillance and treatment strategies.
Publish Date 2026-09-09 09:45
Citation

Ruan Z, Zhu LX, Zeng YY, Lu CH, Guan GX, Wu JW, Li F. Risk factors for recurrence and metastasis of stage IIIC colorectal cancer: A two-center retrospective cohort study. World J Gastrointest Oncol 2026; 18(9): 121235

URL https://www.wjgnet.com/1948-5204/full/v18/i9/121235.htm
DOI https://doi.org/10.4251/wjgo.121235
Full Article (PDF) WJGO-18-121235-with-cover.pdf
STROBE Statement 121235-STROBE-statement.pdf
Manuscript File 121235_Auto_Edited_054654.docx
Answering Reviewers 121235-answering-reviewers.pdf
Audio Core Tip 121235-audio.wav
Biostatistics Review Certificate 121235-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121235-conflict-of-interest-statement.pdf
Copyright License Agreement 121235-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121235-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121235-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121235-non-native-speakers.pdf
Peer-review Report 121235-peer-reviews.pdf
Scientific Misconduct Check 121235-scientific-misconduct-check.png
CrossCheck Report 121235-crosscheck-report.pdf