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5/27/2026 8:10:56 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 121264
Country India
Received
2026-03-22 03:22
Peer-Review Started
2026-03-22 03:23
First Decision by Editorial Office Director
2026-04-15 09:00
Return for Revision
2026-04-15 09:00
Revised
2026-04-24 19:32
Publication Fee Transferred
Second Decision by Editor
2026-05-11 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-11 08:36
Articles in Press
2026-05-11 08:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-19 08:38
Publish the Manuscript Online
2026-05-27 08:10
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Fructose malabsorption associated with functional abdominal bloating: Case-control study
Manuscript Source Invited Manuscript
All Author List Arivarasan Kulandaivelu, Venkatesh Vaithiyam, Kartik Mehta, Ravi Teja Reddy, Aarushi Ahuja, Nikhil Sirohi, Ujjwal Sonika, Ashok Dalal, Ajay Kumar, Amarender Singh Puri and Sanjeev Sachdeva
ORCID
Author(s) ORCID Number
Venkatesh Vaithiyam http://orcid.org/0000-0002-0713-5501
Ajay Kumar http://orcid.org/0000-0002-5877-4610
Sanjeev Sachdeva http://orcid.org/0000-0002-5588-1111
Funding Agency and Grant Number
Corresponding Author Sanjeev Sachdeva, Director, Head, Professor, Department of Gastroenterology, Govind Ballabh Pant Institute of Post Graduate Medical Education and Research, JL Nehru Marg, New Delhi 110002, Delhi, India. sanjeevgastro@rediffmail.com
Key Words Fructose malabsorption; Fructose intolerance; Functional bloating; Small intestinal bacterial overgrowth; Methane producer
Core Tip Fructose malabsorption (FM) is increasingly recognised as a contributor to functional gastrointestinal symptoms. In this case-control study, FM was significantly more common in patients with functional abdominal bloating than in healthy controls (29% vs 3%). A subset of patients with functional bloating who tested negative for the fructose hydrogen breath test (FHBT) had symptoms during the FHBT, suggesting a mechanism beyond fructose malabsorption, such as visceral hypersensitivity, in the pathogenesis of functional bloating. Female sex was identified as an independent predictor. These findings suggest that FM may be an important, potentially modifiable factor in patients presenting with functional bloating.
Publish Date 2026-05-27 08:10
Citation

Kulandaivelu A, Vaithiyam V, Mehta K, Reddy RT, Ahuja A, Sirohi N, Sonika U, Dalal A, Kumar A, Puri AS, Sachdeva S. Fructose malabsorption associated with functional abdominal bloating: Case-control study. World J Gastrointest Pharmacol Ther 2026; 17(2): 121264

URL https://www.wjgnet.com/2150-5349/full/v17/i2/121264.htm
DOI https://dx.doi.org/10.4292/wjgpt.v17.i2.121264
Full Article (PDF) WJGPT-17-121264-with-cover.pdf
STROBE Statement 121264-STROBE-statement.pdf
Manuscript File 121264_Auto_Edited_062330.docx
Answering Reviewers 121264-answering-reviewers.pdf
Audio Core Tip 121264-audio.mp3
Biostatistics Review Certificate 121264-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121264-conflict-of-interest-statement.pdf
Copyright License Agreement 121264-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121264-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121264-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121264-non-native-speakers.pdf
Peer-review Report 121264-peer-reviews.pdf
Scientific Misconduct Check 121264-scientific-misconduct-check.png
Scientific Editor Work List 121264-scientific-editor-work-list.pdf
CrossCheck Report 121264-crosscheck-report.pdf