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Publication Name World Journal of Biological Chemistry
Manuscript ID 121278
Country Greece
Received
2026-03-22 02:56
Peer-Review Started
2026-03-22 02:57
First Decision by Editorial Office Director
2026-04-22 10:56
Return for Revision
2026-04-22 10:56
Revised
2026-05-19 07:48
Publication Fee Transferred
Second Decision by Editor
2026-06-16 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-16 09:12
Articles in Press
2026-06-16 09:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-27 09:26
Publish the Manuscript Online
2026-09-03 02:49
ISSN 1949-8454 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Minireviews
Article Title Calcified coronary artery disease: Mechanisms, risk factors and clinical consequences
Manuscript Source Invited Manuscript
All Author List Nikolaos Ktenopoulos, Anastasios Apostolos, Theoni Theodoropoulou, Paschalis Karakasis, Panagiotis Iliakis, Nikolaos Tsiamis, Nikias Milaras, Ioannis Skalidis, Kiriaki Evdaimon, Marios Sagris, Maria Drakopoulou, Andreas Synetos, George Latsios, Konstantinos Tsioufis and Konstantinos Toutouzas
ORCID
Author(s) ORCID Number
Nikolaos Ktenopoulos http://orcid.org/0000-0002-0995-7015
Nikias Milaras http://orcid.org/0000-0001-7312-0976
Marios Sagris http://orcid.org/0000-0002-3473-1368
Maria Drakopoulou http://orcid.org/0000-0002-0022-0332
George Latsios http://orcid.org/0000-0002-9133-9258
Konstantinos Tsioufis http://orcid.org/0000-0002-7636-6725
Funding Agency and Grant Number
Corresponding Author Nikolaos Ktenopoulos, FESC, MD, First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Vasilissis Sofias 114, Athens 11527, Greece. nikosktenop@gmail.com
Key Words Coronary artery calcification; Atherosclerosis; Intravascular imaging; Calcified nodule; Percutaneous coronary intervention
Core Tip Coronary artery calcification reflects both atherosclerotic burden and lesion complexity. While extensive sheet-like calcium is often associated with stable plaque, spotty calcification and eruptive calcified nodules may increase thrombotic risk. Intracoronary imaging with intravascular ultrasound and optical coherence tomography enables accurate calcium assessment and guides appropriate lesion preparation. A phenotype-driven approach may improve stent expansion and outcomes in patients undergoing percutaneous coronary intervention for calcified coronary artery disease.
Publish Date 2026-09-03 02:49
Citation

Ktenopoulos N, Apostolos A, Theodoropoulou T, Karakasis P, Iliakis P, Tsiamis N, Milaras N, Skalidis I, Evdaimon K, Sagris M, Drakopoulou M, Synetos A, Latsios G, Tsioufis K, Toutouzas K. Calcified coronary artery disease: Mechanisms, risk factors and clinical consequences. World J Biol Chem 2026; 17(3): 121278
URL https://www.wjgnet.com/1949-8454/full/v17/i3/121278.htm
DOI https://doi.org/10.4331/wjbc.121278
Full Article (PDF) WJBC-17-121278-with-cover.pdf
Manuscript File 121278_Auto_Edited_023730.docx
Answering Reviewers 121278-answering-reviewers.pdf
Audio Core Tip 121278-audio.mp3
Conflict-of-Interest Disclosure Form 121278-conflict-of-interest-statement.pdf
Copyright License Agreement 121278-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 121278-non-native-speakers.pdf
Peer-review Report 121278-peer-reviews.pdf
Scientific Misconduct Check 121278-scientific-misconduct-check.png
CrossCheck Report 121278-crosscheck-report.pdf
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