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Articles Published Processes
7/9/2026 6:58:22 AM | Browse: 0 | Download: 0
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Received |
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2026-03-23 00:31 |
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Peer-Review Started |
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2026-03-24 06:03 |
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First Decision by Editorial Office Director |
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2026-04-15 07:53 |
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Return for Revision |
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2026-04-15 07:53 |
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Revised |
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2026-04-17 13:14 |
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Publication Fee Transferred |
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2026-04-20 13:03 |
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Second Decision by Editor |
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2026-05-14 02:59 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-21 08:42 |
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Articles in Press |
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2026-05-21 08:42 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-08 09:47 |
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Publish the Manuscript Online |
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2026-07-09 06:58 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Review |
| Article Title |
Effects of hyperglycemia on the bone microenvironment in diabetic osteoporosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bo Li, Wei Wei, Yan-Long Zhang and Xi-Xu Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xi-Xu Zhang, Professor, Department of Endocrinology, The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 60 Huanghe North Street, Shenyang 261000, Liaoning Province, China. 13287683505@163.com |
| Key Words |
Diabetic osteoporosis; Bone microenvironment; Hyperglycemia; Oxidative stress; Inflammation |
| Core Tip |
Diabetic osteoporosis (DOP) poses a major health challenge, elevating fracture risk. Chronic hyperglycemia is central to DOP pathogenesis, instigating oxidative stress via excessive reactive oxygen species and advanced glycation end products, plus inflammation involving the nuclear factor-kappa B signaling pathway within the bone microenvironment. This disrupts bone remodeling. Understanding these molecular mechanisms is crucial for developing innovative prevention and treatment strategies for DOP. |
| Publish Date |
2026-07-09 06:58 |
| Citation |
Li B, Wei W, Zhang YL, Zhang XX. Effects of hyperglycemia on the bone microenvironment in diabetic osteoporosis. World J Diabetes 2026; 17(7): 121312
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i7/121312.htm |
| DOI |
https://doi.org/10.4239/wjd.121312 |
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