BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/7/2026 2:26:30 AM | Browse: 0 | Download: 0
 |
Received |
|
2026-03-23 02:09 |
|
Peer-Review Started |
|
2026-03-23 02:10 |
|
First Decision by Editorial Office Director |
|
2026-04-28 01:54 |
|
Return for Revision |
|
2026-04-28 01:54 |
|
Revised |
|
2026-05-09 23:32 |
|
Publication Fee Transferred |
|
2026-05-13 20:26 |
|
Second Decision by Editor |
|
2026-06-17 02:39 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-06-17 07:44 |
|
Articles in Press |
|
2026-06-17 07:44 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-08-07 01:49 |
|
Publish the Manuscript Online |
|
2026-09-07 02:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Long-term comparative effectiveness of first-line infliximab vs corticosteroids in ulcerative colitis: Remission and colectomy risk
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hossam M Elsaadany, Basem Abd El-Hamid, Emad A Elewesy, Mohamed I Mansour, Wafaa M Abdelghany, Maged A H Shoukeer, Mohamed Khalaf, Sameh M Eid and Mohammed T Almaghraby |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Hossam M Elsaadany, Consultant, MD, Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Al-Bahr Street, Third District, New Damietta 34517, Damietta, Egypt. dr.saadany2019@gmail.com |
| Key Words |
Ulcerative colitis; Infliximab; Corticosteroids; Biologic therapy; Long-term outcomes; Colectomy |
| Core Tip |
This prospective multicenter study compared first-line infliximab with intravenous corticosteroids in patients with moderate-to-severe ulcerative colitis. Early use of infliximab was associated with higher rates of sustained clinical, endoscopic, and histologic remission, along with a significantly reduced risk of colectomy over long-term follow-up. In contrast, intravenous corticosteroids was linked to lower remission durability and higher rates of severe adverse events. These findings support a shift toward early biologic therapy in selected high-risk patients to improve long-term outcomes and reduce steroid-related complications. |
| Publish Date |
2026-09-07 02:26 |
| Citation |
Elsaadany HM, Abd El-Hamid B, Elewesy EA, Mansour MI, Abdelghany WM, Shoukeer MAH, Khalaf M, Eid SM, Almaghraby MT. Long-term comparative effectiveness of first-line infliximab vs corticosteroids in ulcerative colitis: Remission and colectomy risk. World J Gastroenterol 2026; 32(38): 121333
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i38/121333.htm |
| DOI |
https://doi.org/10.3748/wjg.121333 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
