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10/15/2026 5:45:55 AM | Browse: 1 | Download: 3
Publication Name World Journal of Gastroenterology
Manuscript ID 121414
Country China
Received
2026-03-25 02:14
Peer-Review Started
2026-03-25 02:14
First Decision by Editorial Office Director
2026-04-28 02:18
Return for Revision
2026-04-28 02:18
Revised
2026-05-18 13:59
Publication Fee Transferred
2026-05-22 07:17
Second Decision by Editor
2026-06-25 02:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-25 06:53
Articles in Press
2026-06-25 06:53
Edit the Manuscript by Language Editor
2026-07-13 17:47
Typeset the Manuscript
2026-08-31 15:04
Publish the Manuscript Online
2026-10-15 05:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Decade of decline: Unraveling Helicobacter pylori trends in Northwest China
Manuscript Source Unsolicited Manuscript
All Author List Zi-Qin Zeng, Hai-Yan Yang, Liu-Ying He, Ceng Sun, Jin-Hai Wang, Lei Dong, Jun Gong, Lu Li and Ping Zhao
ORCID
Author(s) ORCID Number
Lu Li http://orcid.org/0009-0009-2873-9521
Ping Zhao http://orcid.org/0000-0002-5817-1561
Funding Agency and Grant Number
Corresponding Author Ping Zhao, Chief Physician, MD, Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi’an 710004, Shaanxi Province, China. peggyzhao@163.com
Key Words Helicobacter pylori infection; Prevalence; Trend analysis; Sex differences; Age
Core Tip In this large-scale study, trends in Helicobacter pylori infection in northwest China over a decade were analyzed using data from 69633 outpatients. Our study identified three main findings. First, infection rates declined across all the subgroups. Second, there was no significant difference in infection rates between the two sexes initially; however, infection rates among females declined faster than those among males did over time, leading to the emergence and progressive widening of sex disparity. Third, age and infection risk exhibited a nonlinear relationship with an inflection point. These findings provide evidence to guide targeted gastric cancer prevention strategies.
Publish Date 2026-10-15 05:45
Citation

Zeng ZQ, Yang HY, He LY, Sun C, Wang JH, Dong L, Gong J, Li L, Zhao P. Decade of decline: Unraveling Helicobacter pylori trends in Northwest China. World J Gastroenterol 2026; 32(45): 121414

URL https://www.wjgnet.com/1007-9327/full/v32/i45/121414.htm
DOI https://doi.org/10.3748/wjg.121414
Full Article (PDF) WJG-32-121414-with-cover.pdf
STROBE Statement 121414-STROBE-statement.pdf
Manuscript File 121414_Auto_Edited_010349.docx
Answering Reviewers 121414-answering-reviewers.pdf
Audio Core Tip 121414-audio.mp3
Biostatistics Review Certificate 121414-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121414-conflict-of-interest-statement.pdf
Copyright License Agreement 121414-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121414-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121414-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121414-non-native-speakers.pdf
Peer-review Report 121414-peer-reviews.pdf
Scientific Misconduct Check 121414-scientific-misconduct-check.png
CrossCheck Report 121414-crosscheck-report.pdf