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Publication Name World Journal of Clinical Oncology
Manuscript ID 121496
Country China
Received
2026-03-30 02:56
Peer-Review Started
2026-03-31 06:59
First Decision by Editorial Office Director
2026-04-15 08:03
Return for Revision
2026-04-15 08:03
Revised
2026-05-05 07:02
Publication Fee Transferred
2026-05-09 09:19
Second Decision by Editor
2026-06-04 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-04 08:45
Articles in Press
2026-06-04 08:45
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-10 08:19
Publish the Manuscript Online
2026-06-22 08:41
ISSN 2218-4333 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Lymph node extramedullary hematopoiesis in breast cancer patients receiving neoadjuvant chemotherapy combined with immunotherapy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ping Xing, Zhi-Gang Chen, Hai-Li Jin, Hua-Rong Luo, Mei-Fu Gan and Jian Huang
ORCID
Author(s) ORCID Number
Zhi-Gang Chen http://orcid.org/0000-0001-8903-7042
Mei-Fu Gan http://orcid.org/0000-0002-8143-100x
Funding Agency and Grant Number
Corresponding Author Mei-Fu Gan, Department of Pathology, Taizhou Hospital of Zhejiang Province, Department of Pathology, Taizhou Hospital, Taizhou 318000, China; E-mail: Ganmf@enzemed.com., Linhai 318000, Zhejiang Province, China. ganmf@enzemed.com
Key Words Breast cancer; Neoadjuvant immuno-chemotherapy; PD-1 inhibitor; Extramedullary hematopoiesis; Axillary lymph node
Core Tip This is the first case report of trilineage extramedullary hematopoiesis (EMH) in axillary lymph nodes after neoadjuvant chemoimmunotherapy with a PD-1 inhibitor for triple-negative breast cancer. It highlights a benign mimic of malignancy, emphasizes granulocyte colony-stimulating factor as an initiator of EMH, and speculatively links PD-1 blockade to EMH persistence. Recognition prevents misdiagnosis and underscores systemic therapy effects.
Publish Date 2026-06-22 08:41
Citation

Xing P, Chen ZG, Jin HL, Luo HR, Gan MF, Huang J. Lymph node extramedullary hematopoiesis in breast cancer patients receiving neoadjuvant chemotherapy combined with immunotherapy: A case report. World J Clin Oncol 2026; 17(6): 121496

URL https://www.wjgnet.com/2218-4333/full/v17/i6/121496.htm
DOI https://doi.org/10.5306/wjco.121496
Full Article (PDF) WJCO-17-121496-with-cover.pdf
CARE Checklist–2016 121496-CARE-Checklist-2016.pdf
Manuscript File 121496_Auto_Edited_055303.docx
Answering Reviewers 121496-answering-reviewers.pdf
Audio Core Tip 121496-audio.m4a
Conflict-of-Interest Disclosure Form 121496-conflict-of-interest-statement.pdf
Copyright License Agreement 121496-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 121496-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 121496-non-native-speakers.pdf
Peer-review Report 121496-peer-reviews.pdf
Scientific Misconduct Check 121496-scientific-misconduct-check.png
Scientific Editor Work List 121496-scientific-editor-work-list.pdf
CrossCheck Report 121496-crosscheck-report.pdf