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11/3/2026 4:47:28 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 121570
Country China
Received
2026-03-27 02:06
Peer-Review Started
2026-03-27 02:07
First Decision by Editorial Office Director
2026-04-10 10:26
Return for Revision
2026-04-10 10:26
Revised
2026-04-18 13:52
Publication Fee Transferred
Second Decision by Editor
2026-06-26 02:16
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-26 06:07
Articles in Press
2026-06-26 06:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-21 02:39
Publish the Manuscript Online
2026-11-03 04:47
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Cadherin-17: A potential biomarker for early detection in pancreatic adenocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List William C Cho, Wing S Yu, Tsz C Hon, Elaine T Y Cheung, Xiao Q Wang, Dennis A Wong, Cesar S C Wong, Wah Cheuk and John M Luk
ORCID
Author(s) ORCID Number
William C Cho http://orcid.org/0000-0003-4174-4586
Funding Agency and Grant Number
Corresponding Author William C Cho, PhD, Senior Scientist, Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR , China. chocs@ha.org.hk
Key Words Biomarker; Cadherin-17; Carbohydrate antigen 19-9; Early detection; Pancreatic adenocarcinoma; Prognosis
Core Tip In this pilot study, cadherin-17 (CDH17) was markedly upregulated in pancreatic adenocarcinoma tissue, and its soluble form in plasma distinguished early-stage patients from healthy controls with 86% sensitivity and specificity. These findings point to the biomarker panel consisting of CDH17 and carbohydrate antigen 19-9 offers a possible strategy to address the pressing need for both earlier detection and monitoring disease burden in this malignancy.
Publish Date 2026-11-03 04:47
Citation

Cho WC, Yu WS, Hon TC, Cheung ETY, Wang XQ, Wong DA, Wong CSC, Cheuk W, Luk JM. Cadherin-17: A potential biomarker for early detection in pancreatic adenocarcinoma. World J Gastroenterol 2026; 32(48): 121570

URL https://www.wjgnet.com/1007-9327/full/v32/i48/121570.htm
DOI https://doi.org/10.3748/wjg.121570
Full Article (PDF) WJG-32-121570-with-cover.pdf
Manuscript File 121570_Auto_Edited_012214.docx
Answering Reviewers 121570-answering-reviewers.pdf
Audio Core Tip 121570-audio.mp3
Biostatistics Review Certificate 121570-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121570-conflict-of-interest-statement.pdf
Copyright License Agreement 121570-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121570-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121570-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121570-non-native-speakers.pdf
Peer-review Report 121570-peer-reviews.pdf
Scientific Misconduct Check 121570-scientific-misconduct-check.png
CrossCheck Report 121570-crosscheck-report.pdf