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Articles Published Processes
10/20/2026 3:52:43 AM | Browse: 3 | Download: 0
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Received |
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2026-04-13 01:23 |
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Peer-Review Started |
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2026-04-13 01:24 |
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First Decision by Editorial Office Director |
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2026-04-29 10:13 |
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Return for Revision |
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2026-04-29 10:13 |
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Revised |
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2026-06-05 21:58 |
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Publication Fee Transferred |
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2026-06-16 10:13 |
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Second Decision by Editor |
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2026-09-16 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-09-16 09:34 |
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Articles in Press |
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2026-09-16 09:34 |
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Edit the Manuscript by Language Editor |
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2026-09-24 03:54 |
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Typeset the Manuscript |
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2026-10-13 01:05 |
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Publish the Manuscript Online |
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2026-10-20 03:52 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Gluten-free diet reduces severity of dextran sulfate sodium-induced colitis in BALB/c mice
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
David Funda, Barbora Drabonova, Jaroslav Golias, Tereza Tejklova, Radka Cisarova, Jitka Bartosova and Pavel Drastich |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| AZV Grant from the Ministry of Health of the Czech Republic |
No. NU22-06-00269 |
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| Corresponding Author |
David Funda, MD, PhD, Senior Scientist, Laboratory of Cellular and Molecular Immunology, Institute of Microbiology, Czech Academy of Sciences, Videnska 1083, Prague 140 00, Czech Republic. funda@biomed.cas.cz |
| Key Words |
Gluten-free diet; Inflammatory bowel disease; Colitis; Intestinal inflammation; Nutrition |
| Core Tip |
A gluten-free diet (GFD) markedly attenuated dextran sulfate sodium-induced colitis in BALB/c mice, reducing clinical and histological disease severity. Gluten withdrawal decreased colonic lymphocyte antigen 6C+ monocyte infiltration and promoted anti-inflammatory immune responses, including increased proportions of forkhead box P3+ regulatory T cells and interleukin-10+ T helper cells, as well as γδ T cells. These findings highlight a previously underappreciated role of dietary gluten in intestinal inflammation and support a GFD as a potential non-pharmacological strategy for modulating immune responses in inflammatory bowel disease. |
| Publish Date |
2026-10-20 03:52 |
| Citation |
Funda D, Drabonova B, Golias J, Tejklova T, Cisarova R, Bartosova J, Drastich P. Gluten-free diet reduces severity of dextran sulfate sodium-induced colitis in BALB/c mice. World J Gastroenterol 2026; 32(46): 121572
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i46/121572.htm |
| DOI |
https://doi.org/10.3748/wjg.121572 |
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