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8/13/2026 7:25:31 AM | Browse: 4 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 121652
Country United Kingdom
Received
2026-03-30 07:40
Peer-Review Started
2026-03-30 07:45
First Decision by Editorial Office Director
2026-04-15 09:16
Return for Revision
2026-04-15 09:16
Revised
2026-04-28 03:44
Publication Fee Transferred
Second Decision by Editor
2026-05-21 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-21 08:25
Articles in Press
2026-05-21 08:25
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-06 07:15
Publish the Manuscript Online
2026-08-13 07:25
ISSN 2220-6124 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Systematic Reviews
Article Title From kidney to liver: Are sodium–glucose cotransporter-2 inhibitors emerging as metabolic disease modifiers?
Manuscript Source Invited Manuscript
All Author List Sydney Mpisa and Jonathan Soldera
ORCID
Author(s) ORCID Number
Sydney Mpisa http://orcid.org/0000-0001-5944-8553
Jonathan Soldera http://orcid.org/0000-0001-6055-4783
Funding Agency and Grant Number
Corresponding Author Jonathan Soldera, Tutor, Gastroenterology and Acute Medicine, University of South Wales (in association with Learna Ltd.), University of South Wales, Llantwit Road, Pontypridd, Cardiff CF37 1DL, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com
Key Words Hepatocellular carcinoma; Sodium-glucose transporter 2 inhibitors; Metabolic dysfunction-associated steatotic liver disease; Chronic kidney disease; Metabolic disease modification
Core Tip Sodium-glucose cotransporter-2 inhibitors extend beyond glycaemic control and may modify key pathways of metabolic disease. Evidence from diabetic kidney disease and metabolic dysfunction-associated steatotic liver disease suggests these agents attenuate inflammation and fibrosis, with a potential association with reduced hepatocellular carcinoma incidence. This supports a shift toward integrated, cross-organ metabolic disease modification.
Publish Date 2026-08-13 07:25
Citation

Mpisa S, Soldera J. From kidney to liver: Are sodium–glucose cotransporter-2 inhibitors emerging as metabolic disease modifiers? World J Nephrol 2026; 15(3): 121652

URL https://www.wjgnet.com/2220-6124/full/v15/i3/121652.htm
DOI https://doi.org/10.5527/wjn.121652
Full Article (PDF) WJN-15-121652-with-cover.pdf
PRISMA 2009 Checklist 121652-PRISMA-2009-Checklist.pdf
Manuscript File 121652_Auto_Edited_085607.docx
Answering Reviewers 121652-answering-reviewers.pdf
Audio Core Tip 121652-audio.ogg
Biostatistics Review Certificate 121652-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121652-conflict-of-interest-statement.pdf
Copyright License Agreement 121652-copyright-assignment.pdf
Peer-review Report 121652-peer-reviews.pdf
Scientific Misconduct Check 121652-scientific-misconduct-check.png
Scientific Editor Work List 121652-scientific-editor-work-list.pdf
CrossCheck Report 121652-crosscheck-report.pdf