BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/26/2026 9:50:21 AM | Browse: 0 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 121656
Country United States
Received
2026-03-30 00:55
Peer-Review Started
2026-03-31 07:04
First Decision by Editorial Office Director
2026-04-15 07:58
Return for Revision
2026-04-15 07:58
Revised
2026-05-03 03:40
Publication Fee Transferred
Second Decision by Editor
2026-05-27 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-27 06:19
Articles in Press
2026-05-27 06:19
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-16 01:10
Publish the Manuscript Online
2026-06-26 09:50
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Meta-Analysis
Article Title Tyrosine kinase inhibitors after progression on atezolizumab-bevacizumab in advanced hepatocellular carcinoma: A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Ronald Blanco Montecino, Nehemias Guevara Rodriguez, Noemy Coreas, Daniel Mendoza-Quispe, Yassine Kilani, Syeda Ashna Fatima Kamal, Kamran Qureshi and John M Richart
ORCID
Author(s) ORCID Number
Ronald Blanco Montecino http://orcid.org/0009-0006-9243-2039
Nehemias Guevara Rodriguez http://orcid.org/0000-0003-3808-0803
Noemy Coreas http://orcid.org/0009-0007-4079-5329
Daniel Mendoza-Quispe http://orcid.org/0000-0003-0174-5816
Kamran Qureshi http://orcid.org/0000-0002-0389-7269
Funding Agency and Grant Number
Corresponding Author Ronald Blanco Montecino, MD, Department of Internal Medicine, Saint Barnabas Hospital, CUNY School of Medicine, 4422 Third Avenue, Bronx, NY 10457, United States. ronaldmau94@gmail.com
Key Words Hepatocellular carcinoma; Tyrosine kinase inhibitors; Atezolizumab; Bevacizumab; Second-line therapy; Disease progression; Survival outcomes; Adverse events; Meta-analysis
Core Tip Atezolizumab plus bevacizumab represents the standard first-line therapy for advanced hepatocellular carcinoma; however, treatment options after disease progression remain poorly defined. Tyrosine kinase inhibitors, established prior to the immunotherapy era, are frequently used in this setting, although their effectiveness after prior immunotherapy exposure is not well characterized. Therefore, a comprehensive evaluation of their role is needed. Our meta-analysis assessed the efficacy and safety of tyrosine kinase inhibitors after progression on atezolizumab plus bevacizumab in advanced hepatocellular carcinoma.
Publish Date 2026-06-26 09:50
Citation

Blanco Montecino R, Rodriguez NG, Coreas N, Mendoza-Quispe D, Kilani Y, Kamal SAF, Qureshi K, Richart JM. Tyrosine kinase inhibitors after progression on atezolizumab-bevacizumab in advanced hepatocellular carcinoma: A systematic review and meta-analysis. World J Hepatol 2026; 18(6): 121656

URL https://www.wjgnet.com/1948-5182/full/v18/i6/121656.htm
DOI https://doi.org/10.4254/wjh.121656
Full Article (PDF) WJH-18-121656-with-cover.pdf
PRISMA 2009 Checklist 121656-PRISMA-2009-Checklist.pdf
Manuscript File 121656_Auto_Edited_081833.docx
Answering Reviewers 121656-answering-reviewers.pdf
Audio Core Tip 121656-audio.mp3
Biostatistics Review Certificate 121656-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121656-conflict-of-interest-statement.pdf
Copyright License Agreement 121656-copyright-assignment.pdf
Supplementary Material 121656-supplementary-material.pdf
Peer-review Report 121656-peer-reviews.pdf
Scientific Misconduct Check 121656-scientific-misconduct-check.png
Scientific Editor Work List 121656-scientific-editor-work-list.pdf
CrossCheck Report 121656-crosscheck-report.pdf