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8/20/2026 6:54:15 AM | Browse: 2 | Download: 10
Publication Name World Journal of Stem Cells
Manuscript ID 121713
Country China
Received
2026-04-01 08:23
Peer-Review Started
2026-04-01 08:24
First Decision by Editorial Office Director
2026-04-23 03:26
Return for Revision
2026-04-23 03:26
Revised
2026-05-07 03:57
Publication Fee Transferred
Second Decision by Editor
2026-06-01 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-04 08:51
Articles in Press
2026-06-04 08:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-09 08:35
Publish the Manuscript Online
2026-08-20 06:54
ISSN 1948-0210 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Applying microfluidic techniques for biomaterial and mechanical regulation of mesenchymal stem cells
Manuscript Source Invited Manuscript
All Author List Bing-Qi Song, Jing Du and Xiao-Ming Li
ORCID
Author(s) ORCID Number
Xiao-Ming Li http://orcid.org/0000-0003-3899-7021
Funding Agency and Grant Number
Funding Agency Grant Number
Beijing Natural Science Foundation L251086, L248028
National Natural Science Foundation of China 32571560, 82273500
Corresponding Author Xiao-Ming Li, PhD, Professor, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Key Laboratory of Innovation and Transformation of Advanced Medical Devices of Ministry of Industry and Information Technology, National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering), Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, No. 37 Xueyuan Road, Haidian District, Beijing 100191, China. x.m.li@hotmail.com
Key Words Microfluidic techniques; Mesenchymal stem cells; Biomaterials; Mechanical stress; Single-cell analysis; Three-dimensional cell culture
Core Tip This review organizes microfluidic applications for mesenchymal stem cell research into three sequential stages: Cell quality control to acquire pure subpopulations, microenvironment engineering to replicate the physiological microenvironment, and phenotypic monitoring to track real-time responses. These continuous stages consequently link raw cell preparation to functional readout. To accelerate the clinical adoption of stem cell therapies, we propose that integration, intelligence, and scalable manufacturing are crucial directions for microfluidic systems.
Publish Date 2026-08-20 06:54
Citation

Song BQ, Du J, Li XM. Applying microfluidic techniques for biomaterial and mechanical regulation of mesenchymal stem cells. World J Stem Cells 2026; 18(8): 121713

URL https://www.wjgnet.com/1948-0210/full/v18/i8/121713.htm
DOI https://doi.org/10.4252/wjsc.121713
Full Article (PDF) WJSC-18-121713-with-cover.pdf
Manuscript File 121713_Auto_Edited_020431.docx
Answering Reviewers 121713-answering-reviewers.pdf
Audio Core Tip 121713-audio.m4a
Conflict-of-Interest Disclosure Form 121713-conflict-of-interest-statement.pdf
Copyright License Agreement 121713-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 121713-non-native-speakers.pdf
Peer-review Report 121713-peer-reviews.pdf
Scientific Misconduct Check 121713-scientific-misconduct-check.png
CrossCheck Report 121713-crosscheck-report.pdf