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Publication Name World Journal of Transplantation
Manuscript ID 121739
Country United Kingdom
Received
2026-03-31 03:42
Peer-Review Started
2026-03-31 03:44
First Decision by Editorial Office Director
2026-06-11 02:31
Return for Revision
2026-06-11 02:31
Revised
2026-06-30 21:52
Publication Fee Transferred
Second Decision by Editor
2026-07-23 07:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-27 07:18
Articles in Press
2026-07-27 07:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-27 09:29
Publish the Manuscript Online
2026-09-02 06:21
ISSN 2220-3230 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Systematic Reviews
Article Title Total intravenous anesthesia in kidney transplantation: A narrative review
Manuscript Source Invited Manuscript
All Author List Ervandy Rangganata, Juanita Castellanos De Brigard, Apostolos Prionas, Nagy Habib and Vassilios E Papalois
ORCID
Author(s) ORCID Number
Ervandy Rangganata http://orcid.org/0000-0003-3273-3113
Juanita Castellanos De Brigard http://orcid.org/0009-0006-2911-0395
Apostolos Prionas http://orcid.org/0000-0002-7867-9266
Nagy Habib http://orcid.org/0000-0003-4920-4154
Vassilios E Papalois http://orcid.org/0000-0003-1645-8684
Funding Agency and Grant Number
Corresponding Author Ervandy Rangganata, Doctorate Student, MD, Department of Surgery and Cancer, Imperial College London, Du Cane Road London W12 0HS, London W12 0HS, London, City of, United Kingdom. e.rangganata24@imperial.ac.uk
Key Words Kidney transplantation; Total intravenous anesthesia; Propofol; Volatile anesthesia; Sevoflurane; Ischaemia-reperfusion injury; Delayed graft function; Postoperative recovery
Core Tip This narrative review compares propofol-based total intravenous anaesthesia (TIVA) with volatile anaesthesia in adult kidney transplantation. Across six comparable studies, TIVA delivers haemodynamic stability and graft function equivalent to volatile maintenance, with reproducible advantages in extubation time and postoperative nausea and vomiting—the latter clinically important for reliable early enteral absorption of immunosuppressants. The biomarker signal of reduced tubular stress under propofol from the VAPOR-1 trial has not translated into measurable clinical benefit in low-risk living-donor cohorts. The next critical step is an adequately powered multicentre randomised trial in extended-criteria-donor and donation-after-circulatory-death recipients, with standardised opioid, fluid, and vasopressor protocols.
Publish Date 2026-09-02 06:21
Citation

Rangganata E, Castellanos De Brigard J, Prionas A, Habib N, Papalois VE. Total intravenous anesthesia in kidney transplantation: A narrative review. World J Transplant 2026; 16(3): 121739

URL https://www.wjgnet.com/2220-3230/full/v16/i3/121739.htm
DOI https://doi.org/10.5500/wjt.121739
Full Article (PDF) WJT-16-121739-with-cover.pdf
PRISMA 2009 Checklist 121739-PRISMA-2009-Checklist.pdf
Manuscript File 121739_Auto_Edited_032822.docx
Answering Reviewers 121739-answering-reviewers.pdf
Audio Core Tip 121739-audio.m4a
Biostatistics Review Certificate 121739-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121739-conflict-of-interest-statement.pdf
Copyright License Agreement 121739-copyright-assignment.pdf
Peer-review Report 121739-peer-reviews.pdf
Scientific Misconduct Check 121739-scientific-misconduct-check.png
CrossCheck Report 121739-crosscheck-report.pdf