BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/12/2026 3:43:53 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 121769
Country China
Received
2026-04-01 03:15
Peer-Review Started
2026-04-01 03:16
First Decision by Editorial Office Director
Return for Revision
2026-07-01 03:37
Revised
2026-08-06 13:46
Publication Fee Transferred
2026-09-16 13:34
Second Decision by Editor
2026-10-15 03:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-16 09:02
Articles in Press
2026-10-16 09:02
Edit the Manuscript by Language Editor
2026-10-23 04:06
Typeset the Manuscript
2026-11-02 01:24
Publish the Manuscript Online
2026-11-12 03:43
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Expression and role of the long noncoding RNA Linc00909 in chemoradiotherapy for colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Yong Wu, Yi-Yi Zhang, Bing-Jie Guan, Hua-Jun Cai and Guo-Xian Guan
ORCID
Author(s) ORCID Number
Guo-Xian Guan http://orcid.org/0000-0001-9883-3139
Funding Agency and Grant Number
Funding Agency Grant Number
Fujian Provincial Health Technology Project 2023QNA038
Joint Funds for the Innovation of Science and Technology, Fujian Province 2020Y9125
Fujian Province Finance Project BPB-2023GGX
Corresponding Author Guo-Xian Guan, MD, Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. fjxhggx@163.com
Key Words Colorectal cancer; Linc00909; Neoadjuvant chemoradiotherapy; Prognosis; Therapy resistance
Core Tip Using 196 paired colorectal cancer and adjacent tissues from 30 patients with rectal cancer (19 resistant, 11 sensitive) to neoadjuvant chemoradiotherapy, we assessed Linc00909 expression via real-time polymerase chain reaction and correlated it with survival outcomes. Functional assays in Linc00909-overexpressing SW620 and DLD1 cells - including cholecystokinin-8, flow cytometry, and sphere formation - evaluated proliferation, cell cycle, apoptosis, stemness, and 5-FU/radiotherapy sensitivity. Tumorigenicity was examined in vivo. Bioinformatics and molecular experiments explored Linc00909’s ceRNA mechanism.
Publish Date 2026-11-12 03:43
Citation

Wu Y, Zhang YY, Guan BJ, Cai HJ, Guan GX. Expression and role of the long noncoding RNA Linc00909 in chemoradiotherapy for colorectal cancer. World J Gastrointest Surg 2026; 18(11): 121769

URL https://www.wjgnet.com/1948-9366/full/v18/i11/121769.htm
DOI https://doi.org/10.4240/wjgs.121769
Full Article (PDF) WJGS-18-121769-with-cover.pdf