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8/7/2026 9:40:20 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 121785
Country China
Received
2026-04-14 09:17
Peer-Review Started
2026-04-14 09:18
First Decision by Editorial Office Director
2026-04-23 03:15
Return for Revision
2026-04-23 03:15
Revised
2026-05-07 13:07
Publication Fee Transferred
2026-05-10 13:55
Second Decision by Editor
2026-05-26 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-26 07:14
Articles in Press
2026-05-26 07:14
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-29 09:35
Publish the Manuscript Online
2026-08-07 09:40
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Randomized Controlled Trial
Article Title Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial
Manuscript Source Unsolicited Manuscript
All Author List Ting-Ting Ma, Jun Tong and Mei-Yu Liu
ORCID
Author(s) ORCID Number
Ting-Ting Ma http://orcid.org/0009-0002-9167-3069
Funding Agency and Grant Number
Funding Agency Grant Number
Chronic Disease Management Research Project of National Health Commission Capacity Building and Continuing Education Center No. CWJJMB202510042058
Corresponding Author Mei-Yu Liu, Department of Anesthesiology, Jiangdu People’s Hospital Affiliated to Yangzhou University, No. 100 Jiangzhou Road, Jiangdu District, Yangzhou 225200, Jiangsu Province, China. myliu@yzu.edu.cn
Key Words Hypertension; Gastrointestinal tumors; Surgery; Remimazolam; Myocardial injury after non-cardiac surgery; Cardioprotection
Core Tip This randomized controlled study demonstrates that remimazolam-based anesthesia provides significant cardioprotective effects in elderly hypertensive patients undergoing gastrointestinal tumor surgery. Compared with conventional anesthesia, remimazolam reduces cardiac biomarker levels, improves hemodynamic stability, alleviates postoperative pain and agitation, and lowers the incidence of myocardial injury after non-cardiac surgery. These findings suggest that remimazolam may be a safer anesthetic option in high-risk elderly populations and highlight potential strategies for preventing perioperative cardiac complications.
Publish Date 2026-08-07 09:40
Citation

Ma TT, Tong J, Liu MY. Cardioprotective effects of remimazolam in elderly hypertensive patients undergoing gastrointestinal tumor surgery: A randomized controlled trial. World J Gastrointest Oncol 2026; 18(8): 121785

URL https://www.wjgnet.com/1948-5204/full/v18/i8/121785.htm
DOI https://doi.org/10.4251/wjgo.v18.i8.121785
Full Article (PDF) WJGO-18-121785-with-cover.pdf
CONSORT 2010 Statement 121785-CONSORT-2010-statement.pdf
Manuscript File 121785_Auto_Edited_082817-YJP.docx
Answering Reviewers 121785-answering-reviewers.pdf
Audio Core Tip 121785-audio.m4a
Biostatistics Review Certificate 121785-biostatistics-statement.pdf
Clinical Trial Registration Statement 121785-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 121785-conflict-of-interest-statement.pdf
Copyright License Agreement 121785-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121785-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121785-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121785-non-native-speakers.pdf
Peer-review Report 121785-peer-reviews.pdf
Scientific Misconduct Check 121785-scientific-misconduct-check.png
Scientific Editor Work List 121785-scientific-editor-work-list.pdf
CrossCheck Report 121785-crosscheck-report.pdf