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Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 121790
Country India
Received
2026-04-08 03:25
Peer-Review Started
2026-04-08 03:28
First Decision by Editorial Office Director
2026-04-23 05:05
Return for Revision
2026-04-23 05:05
Revised
2026-05-31 07:20
Publication Fee Transferred
Second Decision by Editor
2026-07-01 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-01 08:36
Articles in Press
2026-07-01 08:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-14 07:04
Publish the Manuscript Online
2026-09-08 03:16
ISSN 2150-5330 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Accuracy of non-invasive tests for diagnosing liver fibrosis and steatosis: A systematic review
Manuscript Source Invited Manuscript
All Author List Saurin R Shukla, Mirza Amer Ali Baig, Arika Pareek, Namita Johari, Yeshika Thapa, Beulah Blessy Kumpati, Shreya Mahesh Nirmal, Ifrah Ayesha Imdad, Durnave Azid, Eniola Aina and Alisha Lakhani
ORCID
Author(s) ORCID Number
Mirza Amer Ali Baig http://orcid.org/0009-0009-6794-7577
Arika Pareek http://orcid.org/0009-0002-2844-9013
Namita Johari http://orcid.org/0009-0009-6195-2906
Yeshika Thapa http://orcid.org/0009-0002-6921-5571
Beulah Blessy Kumpati http://orcid.org/0009-0009-2970-3707
Ifrah Ayesha Imdad http://orcid.org/0009-0008-9570-9376
Durnave Azid http://orcid.org/0009-0005-3902-3378
Alisha Lakhani http://orcid.org/0000-0003-1884-4976
Funding Agency and Grant Number
Corresponding Author Alisha Lakhani, Consultant, Medicine, Shantabaa Medical College and General Hospital, Civil Hospital Campus, Lathi Road, Amreli 365601, Gujarāt, India. alishalakhani@smcgh.edu.in
Key Words Liver fibrosis; Non-invasive test; Chronic liver diseases; Liver biopsy; Gold standard
Core Tip Non-invasive tests are increasingly replacing liver biopsy for fibrosis assessment in chronic liver diseases due to their safety and accessibility. This systematic review highlights that elastography-based modalities provide high diagnostic accuracy for detecting significant fibrosis, while serum biomarkers serve as effective first-line screening tools. Despite variability in cut-off values and study designs, a stepwise approach combining serum and imaging-based non-invasive tests improves diagnostic reliability. Integrating these modalities into clinical practice can reduce the need for invasive procedures while maintaining accurate fibrosis staging and guiding patient management.
Publish Date 2026-09-08 03:16
Citation

Shukla SR, Baig MAA, Pareek A, Johari N, Thapa Y, Kumpati BB, Nirmal SM, Ayesha Imdad I, Azid D, Aina E, Lakhani A. Accuracy of non-invasive tests for diagnosing liver fibrosis and steatosis: A systematic review. World J Gastrointest Pathophysiol 2026; 17(3): 121790

URL https://www.wjgnet.com/2150-5330/full/v17/i3/121790.htm
DOI https://doi.org/10.4291/wjgp.121790
Full Article (PDF) WJGP-17-121790-with-cover.pdf
PRISMA 2009 Checklist 121790-PRISMA-2009-Checklist.pdf
Manuscript File 121790_Auto_Edited_005404.docx
Answering Reviewers 121790-answering-reviewers.pdf
Audio Core Tip 121790-audio.mp3
Biostatistics Review Certificate 121790-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121790-conflict-of-interest-statement.pdf
Copyright License Agreement 121790-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 121790-non-native-speakers.pdf
Peer-review Report 121790-peer-reviews.pdf
Scientific Misconduct Check 121790-scientific-misconduct-check.png
CrossCheck Report 121790-crosscheck-report.pdf