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9/8/2026 3:16:27 AM | Browse: 0 | Download: 0
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Received |
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2026-04-02 00:36 |
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Peer-Review Started |
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2026-04-02 00:38 |
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First Decision by Editorial Office Director |
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2026-04-13 09:45 |
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Return for Revision |
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2026-04-16 04:05 |
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Revised |
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2026-05-06 14:05 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-22 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-22 03:57 |
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Articles in Press |
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2026-06-22 03:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-31 10:00 |
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Publish the Manuscript Online |
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2026-09-08 03:16 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Field of Vision |
| Article Title |
Paradoxical nutrient hyperabsorption despite diarrhea: Insights from jejunal transcriptomic reanalysis in Linghu’s obesity-diarrhea syndrome
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Tong Niu, Xiang-Yao Wang and En-qiang Ling-Hu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
En-qiang Ling-Hu, Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, No. 94 Weijin Road, Beijing 100853, China. linghuenqiang@vip.sina.com |
| Key Words |
Obesity; Chronic diarrhea; Hyperabsorption; Jejunum; Transcriptome |
| Core Tip |
The jejunal mucosa of patients with Linghu’s obesity-diarrhea syndrome exhibits a unique state of “diarrhea-hyperabsorption”, involving fat digestion and absorption, carbohydrate uptake and transport, and protein catabolism. We hypothesize that this hyperabsorption state may be co-induced by physiological compensation, pathological drivers, and microbial dysbiosis. These findings provide a novel perspective for the clinical management of patients with obesity-diarrhea syndrome. |
| Publish Date |
2026-09-08 03:16 |
| Citation |
Niu XT, Wang XY, Ling-Hu EQ. Paradoxical nutrient hyperabsorption despite diarrhea: Insights from jejunal transcriptomic reanalysis in Linghu’s obesity-diarrhea syndrome. World J Gastrointest Pathophysiol 2026; 17(3): 121798
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| URL |
https://www.wjgnet.com/2150-5330/full/v17/i3/121798.htm |
| DOI |
https://doi.org/10.4291/wjgp.121798 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
