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Articles Published Processes
9/22/2026 3:20:36 AM | Browse: 2 | Download: 1
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Received |
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2026-04-02 01:26 |
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Peer-Review Started |
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2026-04-02 01:27 |
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First Decision by Editorial Office Director |
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2026-06-09 08:38 |
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Return for Revision |
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2026-06-09 08:38 |
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Revised |
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2026-06-22 05:13 |
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Publication Fee Transferred |
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2026-07-03 03:54 |
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Second Decision by Editor |
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2026-07-17 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-17 03:35 |
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Articles in Press |
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2026-07-17 03:35 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-31 10:50 |
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Publish the Manuscript Online |
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2026-09-22 03:20 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Advances on mechanisms and structural classification of Chinese herbal monomers against hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Lian Zheng, Pu-Zhao Chen, Tong Yu, Jie Zhang, Bing-Jiu Lu and Bao-Cheng Deng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Sixth Batch of the National Clinical Excellence Training Program for Traditional Chinese Medicine Talents |
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| The Second Cohort of Liaoning Provincial Outstanding Talents in Traditional Chinese Medicine Program |
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| Science Planing Project of Liaoning Province |
No. 2025-BS-0727 |
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| Corresponding Author |
Bing-Jiu Lu, Chief Physician, Department of Hepatology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33 Beiling Street, Huanggu District, Shenyang 110032, Liaoning Province, China. lubingjiu@163.com |
| Key Words |
Hepatocellular carcinoma; Chinese herbal monomers; Flavonoids; Saponins; Apoptosis; Cell cycle arrest; Drug delivery systems; Ferroptosis; Immunomodulation |
| Core Tip |
Hepatocellular carcinoma is a common and deadly liver cancer. This review focuses on active compounds from traditional Chinese herbs, organized by chemical structure. These natural compounds can suppress tumors in multiple ways simultaneously: They induce tumor cell death, block proliferation and metastasis, and modulate the immune microenvironment. By linking chemical structure to biological activity, this review provides a useful guide for developing these compounds into new liver cancer drugs, with an emphasis on recent advances in overcoming translational barriers such as poor bioavailability and lack of clinical evidence. |
| Publish Date |
2026-09-22 03:20 |
| Citation |
Zheng JL, Chen PZ, Yu T, Zhang J, Lu BJ, Deng BC. Advances on mechanisms and structural classification of Chinese herbal monomers against hepatocellular carcinoma. World J Gastroenterol 2026; 32(42): 121805
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i42/121805.htm |
| DOI |
https://doi.org/10.3748/wjg.121805 |
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