BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/13/2026 7:25:31 AM | Browse: 2 | Download: 0
 |
Received |
|
2026-04-03 08:44 |
|
Peer-Review Started |
|
2026-04-03 08:46 |
|
First Decision by Editorial Office Director |
|
2026-05-26 10:12 |
|
Return for Revision |
|
2026-05-26 10:12 |
|
Revised |
|
2026-06-05 10:54 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-06-24 02:41 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-06-24 08:24 |
|
Articles in Press |
|
2026-06-24 08:24 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-08-06 07:14 |
|
Publish the Manuscript Online |
|
2026-08-13 07:25 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Immunofluorescence-based reclassification of idiopathic membranoproliferative glomerulonephritis: Insights from a single-center cohort
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Rahma Rashid, Ranil H Shrestha, Tabassum Elahi, Shaheera Shakeel and Muhammed Mubarak |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Muhammed Mubarak, Department of Histopathology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com |
| Key Words |
End-stage kidney disease; Membranoproliferative glomerulonephritis; Immune complex-mediated membranoproliferative glomerulonephritis; Complement-mediated membranoproliferative glomerulonephritis; Immunofluorescence |
| Core Tip |
Careful subclassification of membranoproliferative glomerulonephritis (MPGN) using immunofluorescence is essential, as immune complex-mediated MPGN and complement-mediated MPGN (C-MPGN) types differ in underlying mechanisms and outcomes. Although clinical and histopathological features at presentation may appear similar, subtle distinctions, such as stronger C3 deposition and lower serum C3 in C-MPGN, may provide a clue for accurate diagnosis. Immune complex-mediated MPGN is more common and tends to achieve higher remission rates, while C-MPGN may carry a poorer prognosis despite comparable progression to end-stage kidney disease. Long-term follow-up and tailored immunosuppressive strategies are critical for both subtypes to optimize renal outcomes and better understand disease trajectories in diverse populations. |
| Publish Date |
2026-08-13 07:25 |
| Citation |
Rashid R, Shrestha RH, Elahi T, Shakeel S, Mubarak M. Immunofluorescence-based reclassification of idiopathic membranoproliferative glomerulonephritis: Insights from a single-center cohort. World J Nephrol 2026; 15(3): 121887
|
| URL |
https://www.wjgnet.com/2220-6124/full/v15/i3/121887.htm |
| DOI |
https://doi.org/10.5527/wjn.121887 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
