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Articles Published Processes
6/12/2026 6:20:01 AM | Browse: 1 | Download: 9
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Received |
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2026-04-08 01:22 |
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Peer-Review Started |
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2026-04-08 01:26 |
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First Decision by Editorial Office Director |
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2026-04-13 09:23 |
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Return for Revision |
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2026-04-13 16:26 |
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Revised |
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2026-04-21 15:52 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-05-13 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-13 07:54 |
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Articles in Press |
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2026-05-13 07:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-29 07:14 |
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Publish the Manuscript Online |
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2026-06-12 06:20 |
| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Patient-reported outcome assessment in heart failure with preserved ejection fraction: A systematic review of semaglutide trials using the Kansas City Cardiomyopathy Questionnaire
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Razan Abdulaal, Luna Maria Khalil, Ali Hteit, Ehab Al Mashtoub, Mariam Allaw, Lynn Hajj, Abbas Taki and Mohamad Tlais |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohamad Tlais, Cardiology, University of Balamand, Hazmieh, Beirut 1100, Beyrouth, Lebanon. mmtlaiss22@gmail.com |
| Key Words |
Heart failure with preserved ejection fraction; Kansas City Cardiomyopathy Questionnaire; Patient-reported outcomes; Quality of life; Systematic review |
| Core Tip |
This systematic review demonstrates that semaglutide improves patient-reported quality of life in obesity-related heart failure with preserved ejection fraction, with blinded randomised trials showing approximately 7-8 Kansas City Cardiomyopathy Questionnaire points of benefit over placebo. The threefold larger effect in the open-label observational cohort reflects expectation bias and residual confounding rather than genuine superiority. Methodological heterogeneity across instruments, doses, and study designs limits cross-study comparisons and highlights the urgent need for standardised patient-reported outcome sets and prospective trial registration in this field. |
| Publish Date |
2026-06-12 06:20 |
| Citation |
Abdulaal R, Khalil LM, Hteit A, Al Mashtoub E, Allaw M, Hajj L, Taki A, Tlais M. Patient-reported outcome assessment in heart failure with preserved ejection fraction: A systematic review of semaglutide trials using the Kansas City Cardiomyopathy Questionnaire. World J Meta-Anal 2026; 14(2): 121918
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| URL |
https://www.wjgnet.com/2308-3840/full/v14/i2/121918.htm |
| DOI |
https://doi.org/10.13105/wjma.v14.i2.121918 |
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