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8/27/2026 8:00:30 AM | Browse: 4 | Download: 0
Publication Name World Journal of Critical Care Medicine
Manuscript ID 122062
Country Canada
Received
2026-04-08 01:08
Peer-Review Started
2026-04-08 01:10
First Decision by Editorial Office Director
2026-06-10 00:36
Return for Revision
2026-06-10 00:36
Revised
2026-06-16 19:42
Publication Fee Transferred
Second Decision by Editor
2026-07-16 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-16 08:42
Articles in Press
2026-07-16 08:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-19 00:45
Publish the Manuscript Online
2026-08-27 08:00
ISSN 2220-3141(online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Systematic Reviews
Article Title Characterizing the molecular landscape of venous congestion
Manuscript Source Invited Manuscript
All Author List Logan R Van Nynatten, Karina Nabieva, Gemma Barber, Jonathan J Moroniti, Alla Iansavitchene, Ross Prager, Marat Slessarev, John Basmaji and Aleksandra Leligdowicz
ORCID
Author(s) ORCID Number
Logan R Van Nynatten http://orcid.org/0009-0001-1207-2250
Karina Nabieva http://orcid.org/0000-0002-2307-7495
Gemma Barber http://orcid.org/0000-0002-5622-9520
Jonathan J Moroniti http://orcid.org/0009-0005-4083-9956
Alla Iansavitchene http://orcid.org/0000-0002-5651-1024
Ross Prager http://orcid.org/0000-0001-8145-8141
Marat Slessarev http://orcid.org/0000-0003-1181-0706
John Basmaji http://orcid.org/0000-0001-9749-1747
Aleksandra Leligdowicz http://orcid.org/0000-0001-6055-4644
Funding Agency and Grant Number
Corresponding Author Aleksandra Leligdowicz, Critical Care Medicine, Western University, Robarts Research Institute, 100 Perth Dr, Room 4220, London, ON, Canada, N6A 3K7, London N6A5A5, Ontario, Canada. aleks.leligdowicz@lhsc.on.ca
Key Words Biomarkers; Venous congestion; Proteomics; Ultrasound; Critical care
Core Tip Clinicians can increasingly identify venous congestion, but they still do not understand its pathobiology. Although congestion is recognized across multiple disease states, the existing literature is largely confined to isolated protein measurements in congested cardiac populations, leaving its broader molecular biology poorly understood. This review reveals a substantial translational gap between physiologic recognition and biological understanding of venous congestion, highlighting the need for high-dimensional molecular studies to define its mechanisms and therapeutic targets.
Publish Date 2026-08-27 08:00
Citation

Van Nynatten LR, Nabieva K, Barber G, Moroniti JJ, Iansavitchene A, Prager R, Slessarev M, Basmaji J, Leligdowicz A. Characterizing the molecular landscape of venous congestion. World J Crit Care Med 2026; 15(3): 122062

URL https://www.wjgnet.com/2220-3141/full/v15/i3/122062.htm
DOI https://doi.org/10.5492/wjccm.122062
Full Article (PDF) WJCCM-15-122062-with-cover.pdf
PRISMA 2009 Checklist 122062-PRISMA-2009-Checklist.pdf
Manuscript File 122062_Auto_Edited_015850.docx
Answering Reviewers 122062-answering-reviewers.pdf
Audio Core Tip 122062-audio.m4a
Biostatistics Review Certificate 122062-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 122062-conflict-of-interest-statement.pdf
Copyright License Agreement 122062-copyright-assignment.pdf
Supplementary Material 122062-supplementary-material.pdf
Peer-review Report 122062-peer-reviews.pdf
Scientific Misconduct Check 122062-scientific-misconduct-check.png
CrossCheck Report 122062-crosscheck-report.pdf