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8/5/2026 7:53:14 AM | Browse: 1 | Download: 0
Publication Name World Journal of Diabetes
Manuscript ID 122101
Country China
Received
2026-04-10 00:42
Peer-Review Started
2026-04-12 23:55
First Decision by Editorial Office Director
2026-04-29 10:33
Return for Revision
2026-04-29 10:33
Revised
2026-05-13 07:54
Publication Fee Transferred
2026-05-21 05:41
Second Decision by Editor
2026-06-17 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-03 05:59
Articles in Press
2026-07-03 05:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-28 00:37
Publish the Manuscript Online
2026-08-05 07:53
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Retrospective Study
Article Title Non-antibody biomarkers for differentiating ketosis-onset diabetes: A retrospective study
Manuscript Source Unsolicited Manuscript
All Author List Si-Qi Pei, Jie-Ling Ren, Li Zhang, Yan-Xia Gao, Xia Yang, Xiang Liu, Su-Ning Li, Ping Liu and Xiao-Yan Xu
ORCID
Author(s) ORCID Number
Ping Liu http://orcid.org/0000-0001-9536-412X
Funding Agency and Grant Number
Corresponding Author Ping Liu, Professor, Department of Endocrinology, Longgang District People’s Hospital of Shenzhen, No. 53 Aixin Road, Yuyuan Community, Longcheng Subdistrict, Shenzhen 518172, Guangdong Province, China. hanner752003@163.com
Key Words Ketosis-onset adult diabetes; Latent autoimmune diabetes in adults; Ketosis-prone; Type 2 diabetes mellitus; Non-antibody biomarkers; Retrospective study
Core Tip This study demonstrates that more than one-quarter of adults presenting with ketosis have latent autoimmune diabetes in adult, highlighting the risk of misclassification. We identify a practical panel of non-antibody biomarkers, including 2 hours C-peptide, high-density lipoprotein cholesterol, gamma-glutamyl transferase, homeostasis model assessment of insulin resistance, alkaline phosphatase, free triiodothyronine, and fasting plasma glucose, that can effectively differentiate latent autoimmune diabetes in adult from ketosis-prone type 2 diabetes mellitus and predict ketosis onset. These readily available indicators provide a cost-effective diagnostic alternative in settings where autoantibody testing is limited, facilitating early classification and personalized treatment strategies.
Publish Date 2026-08-05 07:53
Citation

Pei SQ, Ren JL, Zhang L, Gao YX, Yang X, Liu X, Li SN, Liu P, Xu XY. Non-antibody biomarkers for differentiating ketosis-onset diabetes: A retrospective study. World J Diabetes 2026; 17(8): 122101

URL https://www.wjgnet.com/1948-9358/full/v17/i8/122101.htm
DOI https://doi.org/10.4239/wjd.122101
Full Article (PDF) WJD-17-122101-with-cover.pdf
Manuscript File 122101_Auto_Edited_013511.docx
Answering Reviewers 122101-answering-reviewers.pdf
Audio Core Tip 122101-audio.mp3
Biostatistics Review Certificate 122101-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 122101-conflict-of-interest-statement.pdf
Copyright License Agreement 122101-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 122101-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 122101-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 122101-non-native-speakers.pdf
Supplementary Material 122101-supplementary-material.pdf
Peer-review Report 122101-peer-reviews.pdf
Journal Editor-in-Chief Review Report 122101-journal-editor-in-chief.pdf
Scientific Misconduct Check 122101-scientific-misconduct-check.png
Scientific Editor Work List 122101-scientific-editor-work-list.pdf
CrossCheck Report 122101-crosscheck-report.pdf