| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Changes in liver and spleen stiffness after transarterial chemoembolization for hepatocellular carcinoma and role in predicting hepatic decompensation
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chidkamon Pattarawongpaiboon, Panarat Thaimai, Sangdao Boonkaya, Kanteera Sriyudthsak, Salisa Lertsanguansinchai, Prooksa Ananchuensook, Supachaya Sriphoosanaphan, Nutcha Pinjaroen, Sombat Treeprasertsuk, Piyawat Komolmit and Kessarin Thanapirom |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Gastroenterological Association of Thailand (GAT) |
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| Corresponding Author |
Kessarin Thanapirom, Associate Professor, MD, PhD, Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama IV Road, Pathumwan, Bangkok 10330, Krung Thep Maha Nakhon, Thailand. kessarin.t@chula.ac.th |
| Key Words |
Cirrhosis; Hepatic decompensation; Hepatocellular carcinoma; Liver stiffness; Noninvasive tests; Portal hypertension; Spleen stiffness; Transarterial chemoembolization; Two-dimensional shear wave elastography |
| Core Tip |
This prospective study evaluated the changes in liver stiffness measurements (LSM) and spleen stiffness measurements (SSM) assessed by two-dimensional shear wave elastography and transient elastography in patients with hepatocellular carcinoma undergoing transarterial chemoembolization. Both LSM and SSM showed no significant changes on days 10 and days 30 after the procedure. Importantly, baseline SSM was identified as a significant non-invasive predictor of 6-month hepatic decompensation. Incorporating baseline SSM (> 54 kilopascals) alongside the modified albumin-bilirubin grade can serve as a comprehensive preprocedural risk stratification tool, effectively bridging the prognostic gap, particularly in clinically homogeneous patients with preserved liver function. |
| Publish Date |
2026-09-28 08:29 |
| Citation |
Pattarawongpaiboon C, Thaimai P, Boonkaya S, Sriyudthsak K, Lertsanguansinchai S, Ananchuensook P, Sriphoosanaphan S, Pinjaroen N, Treeprasertsuk S, Komolmit P, Thanapirom K. Changes in liver and spleen stiffness after transarterial chemoembolization for hepatocellular carcinoma and role in predicting hepatic decompensation. World J Gastroenterol 2026; 32(43): 122240
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i43/122240.htm |
| DOI |
https://doi.org/10.3748/wjg.122240 |
