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7/30/2026 7:49:19 AM | Browse: 1 | Download: 0
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Received |
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2026-05-19 10:54 |
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Peer-Review Started |
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2026-05-19 10:54 |
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First Decision by Editorial Office Director |
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2026-06-12 09:35 |
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Return for Revision |
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2026-06-12 09:35 |
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Revised |
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2026-06-25 11:01 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-07-20 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-20 03:29 |
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Articles in Press |
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2026-07-20 03:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-29 02:05 |
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Publish the Manuscript Online |
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2026-07-30 07:49 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Predictive value of serum inflammatory factors combined with p-tau181 for anxiety and depression in Alzheimer’s disease patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xin Hu, Jin Tao, Yun-Li Jiang and Kai Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kai Liu, Department of Clinical Laboratory and Transfusion Medicine, Traditional Chinese Medicine Hospital Dianjiang Chongqing, No. 502 Gongnong Road, Guixi Street, Chongqing 408300, China. liukai891229@163.com |
| Key Words |
Alzheimer disease; Anxiety; Depression; Interleukin-6; Tumor necrosis factor-alpha; Phosphorylated tau; Biomarkers; Retrospective study |
| Core Tip |
Anxiety and depression are common neuropsychiatric complications that markedly worsen the prognosis, as well as the quality of life in patients with Alzheimer’s disease. This study uncovers that the predictive value for anxiety and depression is improved by combining serum inflammatory markers (interleukin-6 and tumor necrosis factor alpha) with p-tau181 instead of individual biomarkers. These findings highlight the importance of comprehensive biomarker assessment as part of standard of care in Alzheimer’s disease to identify at-risk patients for early treatment. |
| Publish Date |
2026-07-30 07:49 |
| Citation |
Hu X, Tao J, Jiang YL, Liu K. Predictive value of serum inflammatory factors combined with p-tau181 for anxiety and depression in Alzheimer’s disease patients. World J Psychiatry 2026; 16(8): 122295
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| URL |
https://www.wjgnet.com/2220-3206/full/v16/i8/122295.htm |
| DOI |
https://doi.org/10.5498/wjp.122295 |
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