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Publication Name World Journal of Experimental Medicine
Manuscript ID 122305
Country India
Received
2026-04-15 06:33
Peer-Review Started
2026-04-15 06:53
First Decision by Editorial Office Director
2026-05-20 10:44
Return for Revision
2026-05-20 10:44
Revised
2026-06-02 11:04
Publication Fee Transferred
Second Decision by Editor
2026-07-02 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-02 07:53
Articles in Press
2026-07-02 07:53
Edit the Manuscript by Language Editor
2026-07-10 02:41
Typeset the Manuscript
2026-08-14 00:30
Publish the Manuscript Online
2026-09-20 03:28
ISSN 2220-315x (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Respiratory System
Manuscript Type Observational Study
Article Title Culture conversion and drug susceptibility in drug resistant pulmonary tuberculosis with type II diabetes mellitus on oral regimens
Manuscript Source Invited Manuscript
All Author List Yogita Vats, Ajay Kumar Verma, Jyoti Bajpai, Surya Kant, Parul Jain, Darshan Bajaj, Anand Srivastava, Ram Avadh Singh Kushwaha, Santosh Kumar, Rajiv Garg, Ankit Kumar and Akshyaya Pradhan
ORCID
Author(s) ORCID Number
Ajay Kumar Verma http://orcid.org/0000-0002-2973-1793
Jyoti Bajpai http://orcid.org/0000-0001-6337-856X
Akshyaya Pradhan http://orcid.org/0000-0002-2360-7580
Funding Agency and Grant Number
Corresponding Author Jyoti Bajpai, Associate Professor, FCCP, Department of Respiratory Medicine, King George’s Medical University, Shahmina Road, Chowk, Lucknow 226003, Uttar Pradesh, India. jyotibajpai33@gmail.com
Key Words Multidrug-resistant pulmonary tuberculosis; Type 2 diabetes mellitus; Sputum culture conversion; Drug susceptibility testing; All-oral longer regimen
Core Tip This study explores how type 2 diabetes mellitus influences the clinical course and treatment response of patients with multidrug-resistant pulmonary tuberculosis receiving all-oral longer regimen. It demonstrates that patients with diabetes present with more severe disease, higher bacillary burden, and distinct drug resistance patterns. A key finding is the significantly delayed sputum culture conversion in diabetic patients as compared to pre-diabetic and non-diabetic groups. This delay is associated with poorer treatment outcomes and higher mortality. In general, the study highlights the critical need for integrated tuberculosis-diabetes management to improve the patient outcomes in high-burden settings.
Publish Date 2026-09-20 03:28
Citation

Vats Y, Verma AK, Bajpai J, Kant S, Jain P, Bajaj D, Srivastava A, Kushwaha RAS, Kumar S, Garg R, Kumar A, Pradhan A. Culture conversion and drug susceptibility in drug resistant pulmonary tuberculosis with type II diabetes mellitus on oral regimens. World J Exp Med 2026; 16(3): 122305

URL https://www.wjgnet.com/2220-315x/full/v16/i3/122305.htm
DOI https://doi.org/10.5493/wjem.122305
Full Article (PDF) WJEM-16-122305-with-cover.pdf
STROBE Statement 122305-STROBE-statement.pdf
Manuscript File 122305_Auto_Edited_015541.docx
Answering Reviewers 122305-answering-reviewers.pdf
Audio Core Tip 122305-audio.m4a
Biostatistics Review Certificate 122305-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 122305-conflict-of-interest-statement.pdf
Copyright License Agreement 122305-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 122305-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 122305-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 122305-non-native-speakers.pdf
Peer-review Report 122305-peer-reviews.pdf
Scientific Misconduct Check 122305-scientific-misconduct-check.png
CrossCheck Report 122305-crosscheck-report.pdf