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Publication Name World Journal of Psychiatry
Manuscript ID 122412
Country China
Received
2026-04-27 03:46
Peer-Review Started
2026-04-27 03:47
First Decision by Editorial Office Director
2026-05-15 10:54
Return for Revision
2026-05-15 10:54
Revised
2026-06-04 14:28
Publication Fee Transferred
2026-06-09 02:59
Second Decision by Editor
2026-06-26 02:16
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-26 05:49
Articles in Press
2026-06-26 05:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-11 01:41
Publish the Manuscript Online
2026-10-10 09:09
ISSN 2220-3206 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology, Clinical
Manuscript Type Retrospective Study
Article Title Do serum biomarker levels correlate with anxiety disorders?
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Ping Li, Hai-Ling Ji, Shu-Yin Luo, Chun-Ying Zhu, Yu-Ting Qiu, Xin-Ling Zhang, Ya-Li Xu and Lei Jiang
ORCID
Author(s) ORCID Number
Xin-Ling Zhang http://orcid.org/0000-0002-0842-3812
Ya-Li Xu http://orcid.org/0009-0001-2672-9938
Funding Agency and Grant Number
Funding Agency Grant Number
Zhejiang Health Information Association Research Program 2025XHZN-Z04
Corresponding Author Ya-Li Xu, Hangzhou Tongchuang Medical Laboratory, Hangzhou Tongchuang Medical Laboratory, Hangzhou Tongchuang Medical Laboratory, Hangzhou 310022, Zhejiang Province, China. yali.xu@tclab.cn
Key Words Anxiety disorder; Violence; Brain-derived neurotrophic factor; Aquaporin 4; Glycogen synthase kinase 3β; Mature brain-derived neurotrophic factor; Brain-derived neurotrophic factor precursor
Core Tip This retrospective study investigated the role of serum biomarkers in distinguishing between healthy controls and patients with anxiety disorders and a history of violence. The case group exhibited reduced levels of serum brain-derived neurotrophic factor (BDNF), mature BDNF, and aquaporin-4, along with elevated levels of BDNF precursor and glycogen synthase kinase-3β. The combined diagnosis biomarker panel demonstrated significant discriminatory capacity (area under the curve = 0.9698). This combined diagnosis holds potential diagnostic value for identifying these patients with anxiety disorders.
Publish Date 2026-10-10 09:09
Citation

Li XP, Ji HL, Luo SY, Zhu CY, Qiu YT, Zhang XL, Xu YL, Jiang L. Do serum biomarker levels correlate with anxiety disorders? World J Psychiatry 2026; 16(10): 122412

URL https://www.wjgnet.com/2220-3206/full/v16/i10/122412.htm
DOI https://doi.org/10.5498/wjp.122412
Full Article (PDF) WJP-16-122412-with-cover.pdf
Manuscript File 122412_Auto_Edited_021524.docx
Answering Reviewers 122412-answering-reviewers.pdf
Audio Core Tip 122412-audio.mp3
Biostatistics Review Certificate 122412-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 122412-conflict-of-interest-statement.pdf
Copyright License Agreement 122412-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 122412-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 122412-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 122412-non-native-speakers.pdf
Peer-review Report 122412-peer-reviews.pdf
Scientific Misconduct Check 122412-scientific-misconduct-check.png
CrossCheck Report 122412-crosscheck-report.pdf