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9/30/2026 1:50:34 AM | Browse: 2 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 122438
Country China
Received
2026-04-20 06:46
Peer-Review Started
2026-04-20 06:46
First Decision by Editorial Office Director
Return for Revision
2026-06-29 02:06
Revised
2026-07-11 15:22
Publication Fee Transferred
2026-07-22 03:12
Second Decision by Editor
2026-07-27 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-28 13:10
Articles in Press
2026-07-28 13:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-17 03:01
Publish the Manuscript Online
2026-09-30 01:50
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Microbiota-nutrition sequential therapy for refractory radiation proctitis: A case report
Manuscript Source Unsolicited Manuscript
All Author List Tao Huang, Yu-Long He, Guang Fu, Ling Chen, Shi-Tao Huang and Li-Ping Liu
ORCID
Author(s) ORCID Number
Tao Huang http://orcid.org/0000-0002-0879-1850
Li-Ping Liu http://orcid.org/0000-0002-8339-0256
Funding Agency and Grant Number
Funding Agency Grant Number
Gansu Provincial Science and Technology Department 20JR5RA35 and 22JR10KA009
Lanzhou Chengguan District Science and Technology Bureau 2020RCCX0030
Gansu Natural Science Foundation 25JRRA567
Corresponding Author Li-Ping Liu, MD, PhD, Professor, Department of Emergency Intensive Care Unit, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China. liulipingldyy@126.com
Key Words Radiation proctitis; Fecal microbiota transplantation; Gut microbiome; Immunomodulatory enteral nutrition; Gut barrier function; Case report
Core Tip This case demonstrates that combining fecal microbiota transplantation (FMT) with immunomodulatory enteral nutrition can achieve sustained clinical remission in refractory radiation proctitis after only two FMT courses, outperforming previous FMT-alone reports that required 4-7 sessions. The concurrent restoration of gut microbiota diversity, enrichment of beneficial genera (Faecalibacterium, Ruminococcus, Bacteroides), and downregulation of pro-inflammatory cytokines suggest a synergistic effect of nutritional support and microbial reconstruction in radiation-induced intestinal injury. These preliminary observations, however, warrant confirmation in larger prospective studies.
Publish Date 2026-09-30 01:50
Citation

Huang T, He YL, Fu G, Chen L, Huang ST, Liu LP. Microbiota-nutrition sequential therapy for refractory radiation proctitis: A case report. World J Gastroenterol 2026; 32(44): 122438

URL https://www.wjgnet.com/1007-9327/full/v32/i44/122438.htm
DOI https://doi.org/10.3748/wjg.122438
Full Article (PDF) WJG-32-122438-with-cover.pdf
CARE Checklist–2016 122438-CARE-Checklist-2016.pdf
Manuscript File 122438_Auto_Edited_022011.docx
Answering Reviewers 122438-answering-reviewers.pdf
Audio Core Tip 122438-audio.mp3
Conflict-of-Interest Disclosure Form 122438-conflict-of-interest-statement.pdf
Copyright License Agreement 122438-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 122438-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 122438-non-native-speakers.pdf
Peer-review Report 122438-peer-reviews.pdf
Scientific Misconduct Check 122438-scientific-misconduct-check.png
CrossCheck Report 122438-crosscheck-report.pdf