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Publication Name World Journal of Psychiatry
Manuscript ID 122462
Country China
Received
2026-04-30 09:23
Peer-Review Started
2026-04-30 09:23
First Decision by Editorial Office Director
2026-06-04 06:19
Return for Revision
2026-06-04 06:19
Revised
2026-06-17 16:12
Publication Fee Transferred
2026-06-25 13:12
Second Decision by Editor
2026-07-01 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-01 03:25
Articles in Press
2026-07-01 03:25
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-17 00:26
Publish the Manuscript Online
2026-10-10 09:09
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology, Clinical
Manuscript Type Prospective Study
Article Title Psychological distress in advanced non-small cell lung cancer: Impact on targeted therapy and quality of life
Manuscript Source Unsolicited Manuscript
All Author List Wen-Jun Chen, Xue-Yang Hu, Sen-Bang Yao, Mao-Xi Chen, Zi-Ran Bi and Huai-Dong Cheng
ORCID
Author(s) ORCID Number
Wen-Jun Chen http://orcid.org/0009-0005-8367-2535
Xue-Yang Hu http://orcid.org/0009-0009-3841-2477
Sen-Bang Yao http://orcid.org/0000-0003-4769-4970
Mao-Xi Chen http://orcid.org/0000-0002-2164-4185
Zi-Ran Bi http://orcid.org/0000-0002-9254-9660
Huai-Dong Cheng http://orcid.org/0000-0001-6422-1257
Funding Agency and Grant Number
Funding Agency Grant Number
the Shenzhen Science and Technology Program JCYJ20240813145301002, JCYJ20250604183455074
the National Natural Science Foundation of China 82573690
Corresponding Author Huai-Dong Cheng, MD, Professor, Department of Oncology, The Second Affiliated Hospital of Anhui Medical University, No. 678 Furong Avenue, Hefei 230000, Anhui Province, China. chd1975ay@126.com
Key Words Psychological distress; Targeted therapy; Quality of life; Non-small cell lung cancer; Prognosis
Core Tip This study is the first to demonstrate that psychological distress significantly impairs the efficacy of targeted therapy and quality of life in patients with advanced non-small cell lung cancer. Patients without distress showed superior objective response rates, disease control rates, and progression-free survival. Psychological distress is a critical factor affecting treatment outcomes, highlighting the need for routine distress screening and psychological support during non-small cell lung cancer targeted therapy.
Publish Date 2026-10-10 09:09
Citation

Chen WJ, Hu XY, Yao SB, Chen MX, Bi ZR, Cheng HD. Psychological distress in advanced non-small cell lung cancer: Impact on targeted therapy and quality of life. World J Psychiatry 2026; 16(10): 122462

URL https://www.wjgnet.com/2220-3206/full/v16/i10/122462.htm
DOI https://doi.org/10.5498/wjp.122462
Full Article (PDF) WJP-16-122462-with-cover.pdf
CONSORT 2010 Statement 122462-CONSORT-2010-statement.pdf
Manuscript File 122462_Auto_Edited_021523.docx
Answering Reviewers 122462-answering-reviewers.pdf
Audio Core Tip 122462-audio.m4a
Biostatistics Review Certificate 122462-biostatistics-statement.pdf
Clinical Trial Registration Statement 122462-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 122462-conflict-of-interest-statement.pdf
Copyright License Agreement 122462-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 122462-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 122462-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 122462-non-native-speakers.pdf
Peer-review Report 122462-peer-reviews.pdf
Scientific Misconduct Check 122462-scientific-misconduct-check.png
CrossCheck Report 122462-crosscheck-report.pdf