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Articles Published Processes
10/9/2026 8:15:13 AM | Browse: 1 | Download: 3
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Received |
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2026-05-15 09:58 |
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Peer-Review Started |
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2026-05-15 09:58 |
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First Decision by Editorial Office Director |
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2026-06-05 03:21 |
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Return for Revision |
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2026-06-05 03:21 |
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Revised |
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2026-06-16 02:54 |
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Publication Fee Transferred |
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2026-06-22 03:23 |
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Second Decision by Editor |
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2026-06-29 02:20 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-29 05:29 |
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Articles in Press |
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2026-06-29 05:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-08 09:30 |
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Publish the Manuscript Online |
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2026-10-09 08:15 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Association between gut microbial dysbiosis and clinical prognosis of advanced colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yun Wang, Yi-Wei Dong, Yang Wang, Yao-Yu Jin, Yu-Xuan Zhou and Yan Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiaxing Peak Discipline - Oncology |
No. 2025-JF-003 |
| Public Welfare Research Program of Jiaxing Municipal Bureau of Science and Technology |
No. 2024AD30031 |
| The Project Supported by TCM Science and Technology Plan of Zhejiang Province, China |
No. 2023ZL699 |
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| Corresponding Author |
Yan Li, Associate Chief Physician, Department of Gastrointestinal Surgery, The First Hospital of Jiaxing (Affiliated Hospital of Jiaxing University), No. 1882 South Middle Ring Road, Jiaxing 314000, Zhejiang Province, China. liyan10647@163.com |
| Key Words |
Advanced colorectal cancer; Gut microbial dysbiosis; Overall survival; Disease-free survival; Response to chemotherapy |
| Core Tip |
This retrospective cohort study conducted a stratified analysis of patients with stage IIIB-IIIC and stage IV advanced colorectal cancer, confirming that gut microbiota dysbiosis – by modulating bile acid metabolism and the tumor immune microenvironment – is not only an independent adverse prognostic factor for overall survival but also significantly reduces the objective response rate to first-line chemotherapy. |
| Publish Date |
2026-10-09 08:15 |
| Citation |
Wang Y, Dong YW, Wang Y, Jin YY, Zhou YX, Li Y. Association between gut microbial dysbiosis and clinical prognosis of advanced colorectal cancer. World J Gastrointest Oncol 2026; 18(10): 122497
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i10/122497.htm |
| DOI |
https://doi.org/10.4251/wjgo.122497 |
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