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Articles Published Processes
11/5/2026 2:51:09 AM | Browse: 3 | Download: 1
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Received |
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2026-04-30 09:20 |
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Peer-Review Started |
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2026-04-30 09:20 |
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First Decision by Editorial Office Director |
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2026-05-22 03:04 |
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Return for Revision |
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2026-05-22 03:04 |
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Revised |
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2026-06-08 08:20 |
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Publication Fee Transferred |
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2026-06-15 06:19 |
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Second Decision by Editor |
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2026-06-25 02:30 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-25 03:54 |
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Articles in Press |
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2026-06-25 03:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-14 09:31 |
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Publish the Manuscript Online |
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2026-11-05 02:51 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Microbial succession driven by Alistipes depletion shapes the mesenchymal and immune-excluded consensus molecular subtype 4 colorectal cancer landscape
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Dong Hu, Chen-Jie Qiu, Zhen-Biao Song, Zi-Wei Xia, Hai-Tao Wang and Hui Geng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hai-Tao Wang, Professor, Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Soochow University, No. 185 Jiqian Street, Changzhou 213000, Jiangsu Province, China. 15961290078@163.com |
| Key Words |
Colorectal cancer; Consensus molecular subtype 4; Microbial succession; Immune exclusion; Alistipes indistinctus; Fusobacterium |
| Core Tip |
Consensus Molecular Subtype 4 colorectal cancer exhibits a unique microbial succession pattern. Depletion of Alistipes indistinctus initiates a cascade of pathogenic events, ultimately making Fusobacterium the dominant microbial taxon. This microbial shift may mediate tumor immune exclusion through extracellular matrix remodelling, indicating considerable potential for these microbial signatures to act as prognostic biomarkers and therapeutic targets for this refractory cancer subtype. |
| Publish Date |
2026-11-05 02:51 |
| Citation |
Hu JD, Qiu CJ, Song ZB, Xia ZW, Wang HT, Geng H. Microbial succession driven by Alistipes depletion shapes the mesenchymal and immune-excluded consensus molecular subtype 4 colorectal cancer landscape. World J Gastrointest Oncol 2026; 18(11): 122507
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i11/122507.htm |
| DOI |
https://doi.org/10.4251/wjgo.122507 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
