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8/13/2026 7:25:30 AM | Browse: 2 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 122565
Country India
Received
2026-04-22 01:57
Peer-Review Started
2026-04-27 10:04
First Decision by Editorial Office Director
2026-06-04 11:34
Return for Revision
2026-06-05 04:56
Revised
2026-06-10 05:17
Publication Fee Transferred
Second Decision by Editor
2026-07-09 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-09 08:14
Articles in Press
2026-07-09 08:14
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-06 07:10
Publish the Manuscript Online
2026-08-13 07:25
ISSN 2220-6124 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Opinion Review
Article Title SLC30A8 (ZnT8) at the crossroads of epigenetics and microRNA regulation in type 2 diabetes and nephropathy
Manuscript Source Invited Manuscript
All Author List Varun Kumar Sharma, Mirza Masroor Ali Beg, Shilpy Singh, Sourabh Kumar Singh and Dharmsheel Shrivastav
ORCID
Author(s) ORCID Number
Mirza Masroor Ali Beg http://orcid.org/0000-0002-4519-721X
Dharmsheel Shrivastav http://orcid.org/0000-0002-2022-3290
Funding Agency and Grant Number
Corresponding Author Dharmsheel Shrivastav, Assistant Professor, PhD, Department of Biotechnology, Microbiology and Forensic Sciences, School of Sciences, Noida International University, Plot 1, Yamuna Expy, Sector 17A, Greater Noida 203201, Uttar Pradesh, India. dharmsheel.shrivastav1@gmail.com
Key Words Diabetic nephropathy; Type 2 diabetes; SLC30A8; Epigenetic; MiRNAs; ZnT8
Core Tip Diabetic nephropathy is a major complication of type 2 diabetes mellitus. This review highlights the emerging role of the miR-375/miR-765–PDX-1–SLC30A8/ZnT8 regulatory axis in β-cell dysfunction and renal injury. Targeting this pathway through epigenetic and gene-based therapies may restore insulin homeostasis and offer novel strategies for diabetic nephropathy management.
Publish Date 2026-08-13 07:25
Citation

Sharma VK, Beg MMA, Singh S, Singh SK, Shrivastav D. SLC30A8 (ZnT8) at the crossroads of epigenetics and microRNA regulation in type 2 diabetes and nephropathy. World J Nephrol 2026; 15(3): 122565

URL https://www.wjgnet.com/2220-6124/full/v15/i3/122565.htm
DOI https://doi.org/10.5527/wjn.122565
Full Article (PDF) WJN-15-122565-with-cover.pdf
Manuscript File 122565_Auto_Edited_085607.docx
Answering Reviewers 122565-answering-reviewers.pdf
Audio Core Tip 122565-audio.mp3
Conflict-of-Interest Disclosure Form 122565-conflict-of-interest-statement.pdf
Copyright License Agreement 122565-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 122565-non-native-speakers.pdf
Peer-review Report 122565-peer-reviews.pdf
Scientific Misconduct Check 122565-scientific-misconduct-check.png
Scientific Editor Work List 122565-scientific-editor-work-list.pdf
CrossCheck Report 122565-crosscheck-report.pdf