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Articles Published Processes
11/3/2026 4:47:27 AM | Browse: 2 | Download: 0
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Received |
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2026-04-24 06:53 |
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Peer-Review Started |
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2026-04-24 06:54 |
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First Decision by Editorial Office Director |
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2026-06-10 08:25 |
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Return for Revision |
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2026-06-10 08:25 |
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Revised |
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2026-07-07 14:49 |
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Publication Fee Transferred |
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2026-07-25 13:16 |
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Second Decision by Editor |
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2026-07-31 02:50 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-31 09:52 |
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Articles in Press |
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2026-07-31 09:52 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-17 02:55 |
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Publish the Manuscript Online |
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2026-11-03 04:47 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
Patients with acute-on-chronic liver failure admitted to the intensive care unit are at high risk of developing stage 3 acute kidney injury (AKI); however, reliable tools for early prediction remain limited. We developed and externally validated the chronic liver failure organ failure-AKI score to predict stage 3 AKI in patients with acute-on-chronic liver failure. The score demonstrated good discrimination and clinical utility, and outperformed the PIRO model and existing prognostic scores in the external validation cohort. We also developed a point-based scoring system and an online calculator to facilitate its implementation in clinical practice. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
CLIF-AKI score predicts KDIGO stage 3 acute kidney injury in intensive care unit patients with acute-on-chronic liver failure
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Nan Wang, You-Wen Tan, Peng-Fei Zhang, Xing-Bei Zhou and Li Zhu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Zhenjiang Science and Technology Plan for Social Development |
SH2024074 |
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| Corresponding Author |
Peng-Fei Zhang, Department of Hepatology, Zhenjiang Third People’s Hospital, Affiliated Zhenjiang Third Hospital of Jiangsu University, No. 300 Daijiamen Road, Zhenjiang 212009, Jiangsu Province, China. jsdxzpf@163.com |
| Key Words |
Acute kidney injury; Acute-on-chronic liver failure; Predictive score; Risk stratification; Intensive care unit |
| Core Tip |
Patients with acute-on-chronic liver failure admitted to the intensive care unit are at high risk of developing stage 3 acute kidney injury (AKI); however, reliable tools for early prediction remain limited. We developed and externally validated the chronic liver failure organ failure-AKI score to predict stage 3 AKI in patients with acute-on-chronic liver failure. The score demonstrated good discrimination and clinical utility, and outperformed the PIRO model and existing prognostic scores in the external validation cohort. We also developed a point-based scoring system and an online calculator to facilitate its implementation in clinical practice. |
| Publish Date |
2026-11-03 04:47 |
| Citation |
Wang N, Tan YW, Zhang PF, Zhou XB, Zhu L. CLIF-AKI score predicts KDIGO stage 3 acute kidney injury in intensive care unit patients with acute-on-chronic liver failure. World J Gastroenterol 2026; 32(48): 122612
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i48/122612.htm |
| DOI |
https://doi.org/10.3748/wjg.122612 |
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