Publication Name	World Journal of Hepatology
Manuscript ID	12268
Country	China

Received	2014-06-29 13:40
Peer-Review Started	2014-07-01 08:33
To Make the First Decision	2014-07-29 11:59
Return for Revision	2014-07-30 13:36
Revised	2014-08-04 20:08
Second Decision	2014-09-10 09:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-10 09:36
Articles in Press	2014-09-10 09:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-30 16:16
Publish the Manuscript Online	2014-10-19 20:39

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Minireviews
Article Title	Nucleos(t)ide analogues to treat hepatitis B virus-related hepatocellular carcinoma after radical resection
Manuscript Source	Invited Manuscript
All Author List	Yang Ke, Lin Wang, Le-Qun Li and Jian-Hong Zhong
Funding Agency and Grant Number
Corresponding Author	Jian-Hong Zhong, MD, PhD, Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, He Di Rd. #71, Nanning 530021, Guangxi Zhuang Autonomous Region, China. zhongjianhong66@163.com
Key Words	Antiviral therapy; Hepatitis B virus; Hepatocellular carcinoma; Liver resection; Nucleos(t)ide analogue; Survival rate
Core Tip	Significant advances have been made in nucleos(t)ide analogue (NA) therapy to treat chronic hepatitis B. However, for patients undergoing radical resection for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), a number of important questions remain undefined, including when NA therapy should be initiated, how long the treatment should continue, and whether NAs can prevent recurrence after radical resection. Here we review the available evidence on these questions in the Medline database. We focus on NA treatment indications, duration, effects on recurrence-free survival and overall survival, and management of NA resistance in patients with HBV-related HCC.
Publish Date	2014-10-19 20:39
Citation	Ke Y, Wang L, Li LQ, Zhong JH. Nucleos(t)ide analogues to treat hepatitis B virus-related hepatocellular carcinoma after radical resection. World J Hepatol 2014; 6(9): 652-659
URL	http://www.wjgnet.com/1948-5182/full/v6/i9/652.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i9.652

Full Article (PDF)	WJH-6-652.pdf
Full Article (Word)	WJH-6-652.doc
Manuscript File	12268-Review.docx
Answering Reviewers	12268-Answering reviewers.pdf
Copyright License Agreement	12268-Copyright assignment.pdf
Peer-review Report	12268-Peer review(s).pdf
Scientific Misconduct Check	12268-CrossCheck.jpg
Scientific Editor Work List	12268-Scientific editor work list.pdf