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7/24/2026 6:11:16 AM | Browse: 1 | Download: 0
Publication Name World Journal of Clinical Oncology
Manuscript ID 122710
Country China
Received
2026-04-28 02:09
Peer-Review Started
2026-04-28 02:33
First Decision by Editorial Office Director
2026-05-22 02:28
Return for Revision
2026-05-22 02:28
Revised
2026-06-10 14:01
Publication Fee Transferred
2026-06-18 15:18
Second Decision by Editor
2026-07-09 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-09 03:14
Articles in Press
2026-07-09 03:14
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-22 01:08
Publish the Manuscript Online
2026-07-24 06:11
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Multicenter nomogram integrating clinicopathological features for prognosis in stage II-III deficient/microsatellite instability-high rectal cancer
Manuscript Source Unsolicited Manuscript
All Author List De-Yao Zhang, Yi-Jun Liao, Xin Tang, Gong Chen and Rong-Xin Zhang
ORCID
Author(s) ORCID Number
De-Yao Zhang http://orcid.org/0000-0002-9654-8905
Yi-Jun Liao http://orcid.org/0009-0002-5294-126X
Xin Tang http://orcid.org/0009-0002-4546-360X
Gong Chen http://orcid.org/0000-0003-1092-2503
Rong-Xin Zhang http://orcid.org/0000-0001-5498-0428
Funding Agency and Grant Number
Corresponding Author Rong-Xin Zhang, MD, Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, No. 651 Dongfeng East Road, Guangzhou 510060, Guangdong Province, China. zhangrx@sysucc.org.cn
Key Words Mismatch repair; Microsatellite instability; Rectal cancer; Lymphovascular invasion; Perineural invasion; Nomogram; Recurrence-free survival
Core Tip Deficient/microsatellite instability-high rectal cancer has distinct biological features, but postoperative risk assessment is still largely based on tumor-node-metastasis stage. This multicenter exploratory cohort highlights lymphovascular invasion as an independent predictor of recurrence-free survival in stage II-III deficient/microsatellite instability-high rectal adenocarcinoma, while perineural invasion showed no independent prognostic value. A preliminary nomogram integrating tumor stage, lymphovascular invasion, perineural invasion, and body mass index offers a practical framework for recurrence risk stratification, but requires external validation before clinical use.
Publish Date 2026-07-24 06:11
Citation

Zhang DY, YJL, Tang X, Chen G, Zhang RX. Multicenter nomogram integrating clinicopathological features for prognosis in stage II-III deficient/microsatellite instability-high rectal cancer. World J Clin Oncol 2026; 17(7): 122710

URL https://www.wjgnet.com/2218-4333/full/v17/i7/122710.htm
DOI https://doi.org/10.5306/wjco.122710
Full Article (PDF) WJCO-17-122710-with-cover.pdf
STROBE Statement 122710-STROBE-statement.pdf
Manuscript File 122710_Auto_Edited_024752.docx
Answering Reviewers 122710-answering-reviewers.pdf
Audio Core Tip 122710-audio.m4a
Biostatistics Review Certificate 122710-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 122710-conflict-of-interest-statement.pdf
Copyright License Agreement 122710-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 122710-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 122710-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 122710-non-native-speakers.pdf
Peer-review Report 122710-peer-reviews.pdf
Scientific Misconduct Check 122710-scientific-misconduct-check.png
Scientific Editor Work List 122710-scientific-editor-work-list.pdf
CrossCheck Report 122710-crosscheck-report.pdf