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Articles Published Processes
7/24/2026 10:16:19 AM | Browse: 2 | Download: 0
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Received |
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2026-05-07 07:48 |
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Peer-Review Started |
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2026-05-07 07:48 |
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First Decision by Editorial Office Director |
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2026-05-22 09:46 |
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Return for Revision |
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2026-05-22 09:46 |
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Revised |
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2026-06-04 15:28 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-30 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-30 07:12 |
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Articles in Press |
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2026-06-30 07:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-08 11:50 |
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Publish the Manuscript Online |
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2026-07-24 10:16 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Otorhinolaryngology |
| Manuscript Type |
Review |
| Article Title |
Stem cell-based strategies for hearing restoration: Current advances and future perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yan-Ji Qu, Jia-Yu Wang, Zhe Wang, Wei Yao and Zhong-Fang Xia |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Funding for Scientific Research Projects from Wuhan Municipal Health Commission |
WX23Q01 |
| Natural Science Foundation of Hubei Province of China |
2023AFB328, 2025AFB091 |
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| Corresponding Author |
Zhong-Fang Xia, Chief, PhD, Department of Otolaryngology, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 100 Xianggang Road, Wuhan 430022, Hubei Province, China. zhfxia2005@163.com |
| Key Words |
Hearing loss; Stem cell; Cochlear organoids; Hair cell regeneration; Extracellular vesicles |
| Core Tip |
Sensorineural hearing loss remains difficult to reverse as current treatments mainly compensate for dysfunction rather than restore damaged cochlear cells. This review highlights recent progress in stem cell-based hearing restoration, focusing on stem cell sources, auditory cell fate regulation, delivery optimization, immune microenvironment modulation, and cochlear organoids. It further emphasizes the emerging value of organoid platforms and cell-free strategies in advancing translational and regenerative therapies for hearing loss. |
| Publish Date |
2026-07-24 10:16 |
| Citation |
Qu YJ, Wang JY, Wang Z, Yao W, Xia ZF. Stem cell-based strategies for hearing restoration: Current advances and future perspectives. World J Stem Cells 2026; 18(7): 122823
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i7/122823.htm |
| DOI |
https://doi.org/10.4252/wjsc.122823 |
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