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8/25/2026 6:38:35 AM | Browse: 4 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 122851
Country China
Received
2026-04-30 03:26
Peer-Review Started
2026-04-30 03:26
First Decision by Editorial Office Director
2026-06-09 10:00
Return for Revision
2026-06-09 10:00
Revised
2026-06-23 08:59
Publication Fee Transferred
2026-06-30 14:39
Second Decision by Editor
2026-07-06 03:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-06 07:36
Articles in Press
2026-07-06 07:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-19 02:53
Publish the Manuscript Online
2026-08-25 06:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Clinical Trial
Article Title Low-dose vs standard-dose minocycline in bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized controlled, noninferiority trial
Manuscript Source Unsolicited Manuscript
All Author List Ya-Na Zhu, Yong-Bing Wang, Lu Li, Ya-Di Ren, Rao-Rao Wang, Ying-Lan Ji, Ya-Ping Wang, Hao-Yu Zhai and Yong Jiang
ORCID
Author(s) ORCID Number
Ya-Na Zhu http://orcid.org/0009-0009-1539-5862
Lu Li http://orcid.org/0000-0003-1078-9730
Ya-Di Ren http://orcid.org/0000-0003-0234-0757
Rao-Rao Wang http://orcid.org/0009-0001-8601-7414
Ying-Lan Ji http://orcid.org/0009-0009-3230-7019
Ya-Ping Wang http://orcid.org/0009-0003-7024-7121
Hao-Yu Zhai http://orcid.org/0009-0001-0734-7950
Yong Jiang http://orcid.org/0000-0001-7402-5129
Funding Agency and Grant Number
Funding Agency Grant Number
Tianjin Municipal Education Commission Scientific Research Program 2023KJ025
Corresponding Author Yong Jiang, PhD, Professor, Department of Gastroenterology, The Second Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Tianjin 300202, China. jiangyong-612@163.com
Key Words Minocycline; Low-dose; Helicobacter pylori; Eradication therapy; Adverse events
Core Tip The optimal dose of minocycline in bismuth-containing quadruple therapy remains uncertain. This study demonstrates that a low-dose minocycline-based regimen is noninferior to the standard-dose regimen in treatment-naïve Helicobacter pylori infection, while offering a superior safety profile and better cost-effectiveness, supporting its clinical utility.
Publish Date 2026-08-25 06:38
Citation

Zhu YN, Wang YB, Li L, Ren YD, Wang RR, Ji YL, Wang YP, Zhai HY, Jiang Y. Low-dose vs standard-dose minocycline in bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized controlled, noninferiority trial. World J Gastroenterol 2026; 32(36): 122851

URL https://www.wjgnet.com/1007-9327/full/v32/i36/122851.htm
DOI https://doi.org/10.3748/wjg.122851
Full Article (PDF) WJG-32-122851-with-cover.pdf
CONSORT 2010 Statement 122851-CONSORT-2010-statement.pdf
Manuscript File 122851_Auto_Edited_024606.docx
Answering Reviewers 122851-answering-reviewers.pdf
Audio Core Tip 122851-audio.mp3
Biostatistics Review Certificate 122851-biostatistics-statement.pdf
Clinical Trial Registration Statement 122851-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 122851-conflict-of-interest-statement.pdf
Copyright License Agreement 122851-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 122851-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 122851-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 122851-non-native-speakers.pdf
Peer-review Report 122851-peer-reviews.pdf
Scientific Misconduct Check 122851-scientific-misconduct-check.png
CrossCheck Report 122851-crosscheck-report.pdf