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11/9/2026 4:15:47 AM | Browse: 1 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 122855
Country South Korea
Received
2026-05-08 06:35
Peer-Review Started
2026-05-08 06:36
First Decision by Editorial Office Director
2026-05-26 09:40
Return for Revision
2026-05-26 09:40
Revised
2026-06-13 06:54
Publication Fee Transferred
2026-06-22 23:29
Second Decision by Editor
2026-07-02 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-02 08:41
Articles in Press
2026-07-02 08:41
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-22 06:44
Publish the Manuscript Online
2026-11-09 04:15
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Longitudinal serum total cholesterol patterns and subsequent clinical relapse in ulcerative colitis
Manuscript Source Unsolicited Manuscript
All Author List Ji-Yeon Kim, Min-Ji Kim, Minjee Kim, Sung Noh Hong, Dong Kyung Chang, Young-Ho Kim, Eun Ran Kim and Ji Eun Kim
ORCID
Author(s) ORCID Number
Ji-Yeon Kim http://orcid.org/0009-0009-0173-1968
Min-Ji Kim http://orcid.org/0000-0001-5102-0536
Minjee Kim http://orcid.org/0000-0003-0838-841X
Sung Noh Hong http://orcid.org/0000-0002-4140-3717
Dong Kyung Chang http://orcid.org/0000-0001-8925-4629
Young-Ho Kim http://orcid.org/0000-0003-1803-2513
Eun Ran Kim http://orcid.org/0000-0002-0495-2565
Ji Eun Kim http://orcid.org/0000-0003-2149-7979
Funding Agency and Grant Number
Corresponding Author Eun Ran Kim, MD, PhD, Professor, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea. er.kim@samsung.com
Key Words Ulcerative colitis; Clinical relapse; Serum total cholesterol; Longitudinal trajectory; Endoscopic improvement
Core Tip Most studies link serum lipid levels, including total cholesterol (TC), to concurrent inflammatory activity, not to changes after endoscopic improvement. In this retrospective cohort of patients with ulcerative colitis, baseline serum TC did not distinguish outcomes, whereas exploratory trajectory analysis showed divergent serial TC patterns according to subsequent clinical relapse status. In the time-varying Cox model, each 1 mmol/L increase in updated TC was associated with a 1.31-fold higher hazard of clinical relapse. Supportive landmark analyses showed similar associations using maximal TC. Serial serum TC patterns may provide complementary information associated with relapse risk.
Publish Date 2026-11-09 04:15
Citation

Kim JY, Kim MJ, Kim M, Hong SN, Chang DK, Kim YH, Kim ER, Kim JE. Longitudinal serum total cholesterol patterns and subsequent clinical relapse in ulcerative colitis. World J Gastroenterol 2027; 33(1): 122855

URL https://www.wjgnet.com/1007-9327/full/v33/i1/122855.htm
DOI https://doi.org/10.3748/wjg.122855
Full Article (PDF) WJG-33-122855-with-cover.pdf