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11/9/2026 4:15:48 AM | Browse: 3 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 122971
Country China
Received
2026-05-07 02:11
Peer-Review Started
2026-05-07 02:12
First Decision by Editorial Office Director
Return for Revision
2026-06-29 02:47
Revised
2026-07-03 16:46
Publication Fee Transferred
2026-07-22 15:02
Second Decision by Editor
2026-07-29 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-29 10:01
Articles in Press
2026-07-29 10:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-29 09:27
Publish the Manuscript Online
2026-11-09 04:15
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Jin-Can Huang, Han-Xuan Wang, Yang Zhao, Xian-Liang Li, Qiang He, Ren Lang and Lin Zhou
ORCID
Author(s) ORCID Number
Qiang He http://orcid.org/0000-0002-5007-5225
Ren Lang http://orcid.org/0000-0002-9712-8232
Lin Zhou http://orcid.org/0000-0001-8055-4203
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82370665
Corresponding Author Lin Zhou, Division of Hepatobiliary and Pancreaticosplenic Surgery, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing 100020, China. richard_fmmu@126.com
Key Words Hepatocellular carcinoma; Nomogram; Liver transplantation; Nutrition; Immunity; Inflammation
Core Tip Although nutritional, immune and inflammatory status affect hepatocellular carcinoma (HCC) prognosis, composite indicators reflecting these factors remain unreported. We retrospectively enrolled 269 HCC patients undergoing liver transplantation and constructed a prognostic immune-inflammatory-nutritional (PIIN) score using least absolute shrinkage and selection operator regression on routine blood test-derived indicators. A PIIN-based prediction model incorporating PIIN score, tumor number, tumor size, alpha fetoprotein and differentiation was also established. A high PIIN score independently predicted worse overall and disease-free survival, showed favorable discrimination, calibration, and clinical utility superior to conventional criteria, and may serve as a practical tool for evaluating post-transplant prognosis in HCC.
Publish Date 2026-11-09 04:15
Citation

Huang JC, Wang HX, Zhao Y, Li XL, He Q, Lang R, Zhou L. Nomogram integrating prognostic immune-inflammatory-nutritional score with clinicopathological parameters for predicting post-transplantation outcomes in hepatocellular carcinoma. World J Gastroenterol 2027; 33(1): 122971

URL https://www.wjgnet.com/1007-9327/full/v33/i1/122971.htm
DOI https://doi.org/10.3748/wjg.122971
Full Article (PDF) WJG-33-122971-with-cover.pdf