| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yukiko Asakawa, Masahiko Ohtaka, Shinya Maekawa, Mitsuharu Fukasawa, Yasuhiro Nakayama, Tatsuya Yamaguchi, Taisuke Inoue, Tomoyoshi Uetake, Minoru Sakamoto, Tadashi Sato, Yoshihiko Kawaguchi, Hideki Fujii, Kunio Mochizuki, Masao Hada, Toshio Oyama, Tomotaka Yasumura, Kosaku Omata, Atsushi Nishiyama, Keiichi Naito, Hideo Hata, Yoshiaki Haba, Kazuyuki Miyata, Haruhisa Saitoh, Yoichi Yamadera, Kazuo Miura, Akira Kawaoi, Tohru Abe, Hajime Tsunoda, Yuji Honda, Masayuki Kurosaki and Nobuyuki Enomoto |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Masahiko Ohtaka, MD, PhD, First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, 1110, Shimokato, Chuo, Yamanashi 409-3898, Japan. motaka@yamanashi.ac.jp |
| Key Words |
Undifferentiated-type early gastric cancer; Lymph node metastasis; Lymphatic involvement; Data-mining analysis; Stratification |
| Core Tip |
The lymph node metastasis (LNM) risk in cases with undifferentiated-type early gastric cancer was evaluated and stratified using preoperatively as well as postoperatively evaluable factors. In preoperatively evaluable factors, the risk of LNM was predicted based on the size and depth and categorized into the low-risk group: mucosal cancer (m) and ≤ 2 cm, 0% (LNM incidence) (95%CI: 0-2.3), the moderate-risk group: m and > 2 cm, 5.6% (95%CI: 2.6-11.7); submucosal invasion (sm) and ≤ 2 cm, 6.0% (95%CI: 3.2-11.1), and the high-risk group: sm and > 2 cm, 19.3% (95%CI: 13.8-26.4). However, when the postoperatively evaluable factor of LI was included, cases with further lower or higher risk could be stratified even in the moderate- and high-risk groups. Some high-risk cases for surgery due to old age and concurrent disease could be reasonably followed-up after resection of the gastric lesion by endoscopic submucosal dissection. |
| Publish Date |
2015-03-09 15:58 |
| Citation |
Asakawa Y, Ohtaka M, Maekawa S, Fukasawa M, Nakayama Y, Yamaguchi T, Inoue T, Uetake T, Sakamoto M, Sato T, Kawaguchi Y, Fujii H, Mochizuki K, Hada M, Oyama T, Yasumura T, Omata K, Nishiyama A, Naito K, Hata H, Haba Y, Miyata K, Saitoh H, Yamadera Y, Miura K, Kawaoi A, Abe T, Tsunoda H, Honda Y, Kurosaki M, Enomoto N. Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer. World J Gastroenterol 2015; 21(9): 2683-2692 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i9/2683.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i9.2683 |
