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Publication Name World Journal of Gastroenterology
Manuscript ID 123195
Country China
Received
2026-05-12 05:56
Peer-Review Started
2026-05-12 05:57
First Decision by Editorial Office Director
2026-06-05 08:55
Return for Revision
2026-06-05 08:55
Revised
2026-06-27 18:50
Publication Fee Transferred
2026-07-20 07:26
Second Decision by Editor
2026-08-13 02:29
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-14 09:21
Articles in Press
2026-08-14 09:21
Edit the Manuscript by Language Editor
2026-08-20 18:24
Typeset the Manuscript
2026-09-14 01:42
Publish the Manuscript Online
2026-11-11 05:49
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Computer Science, Artificial Intelligence
Manuscript Type Retrospective Study
Article Title Integrating immune-inflammatory and nutritional indicators into machine learning-driven risk stratification for colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Lang Wang, Chang Liu, Jian Xie, Jin-Shan Liu, Xiong Zhou, Fei Liu, Chen-Yu Xiang, Jun-Nan Zhao, Xu-Rui Liu, Xiao-Yu Liu, Bing Kang, Yong Cheng and Dong Peng
ORCID
Author(s) ORCID Number
Fei Liu http://orcid.org/0000-0002-4022-0732
Xu-Rui Liu http://orcid.org/0000-0002-6069-2104
Xiao-Yu Liu http://orcid.org/0000-0001-9448-4592
Bing Kang http://orcid.org/0000-0003-4026-4070
Yong Cheng http://orcid.org/0000-0002-0161-435X
Dong Peng http://orcid.org/0000-0003-4050-4337
Funding Agency and Grant Number
Funding Agency Grant Number
CQMU Program for Youth Innovation in Future Medicine No. W0190
Natural Science Foundation of Chongqing, China No. CSTB2024NSCQ-MSX0098
Corresponding Author Dong Peng, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuanjiagang, Yuzhong District, Chongqing 400016, China. carry_dong@hospital.cqmu.edu.cn
Key Words Colorectal cancer; Immune-inflammatory and nutritional indicators; Metabolic; Post-operative complications; Overall survival; Machine learning
Core Tip This multicenter cohort study included 10205 patients with colorectal cancer (CRC) who underwent radical surgery. We systematically evaluated systemic inflammation- and nutrition-related indicators in relation to postoperative complications and overall survival, and further assessed metabolic dysfunction indices in a sub-cohort. Machine learning models were developed and externally validated, with gradient boosting survival analysis showing stable performance across centers. These findings support the integration of inflammatory, nutritional, and metabolic indicators into individualized risk stratification for CRC.
Publish Date 2026-11-11 05:49
Citation

Wang L, Liu C, Xie J, Liu JS, Zhou X, Liu F, Xiang CY, Zhao JN, Liu XR, Liu XY, Kang B, Cheng Y, Peng D. Integrating immune-inflammatory and nutritional indicators into machine learning-driven risk stratification for colorectal cancer. World J Gastroenterol 2027; 33(2): 123195

URL https://www.wjgnet.com/1007-9327/full/v33/i2/123195.htm
DOI https://doi.org/10.3748/wjg.123195
Full Article (PDF) WJG-33-123195-with-cover.pdf