Publication Name	World Journal of Gastroenterology
Manuscript ID	1232
Country	China

Received	2012-11-23 07:14
Peer-Review Started	2012-11-26 19:06
To Make the First Decision	2013-03-22 17:16
Return for Revision	2013-03-27 10:30
Revised	2013-04-16 20:20
Second Decision	2013-06-19 12:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-06-20 00:47
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-17 09:08
Publish the Manuscript Online	2013-07-29 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Helicobacter pylori and Crohn's disease: A retrospective single-center study from China
Manuscript Source	Invited Manuscript
All Author List	Zun Xiang, Yi-Peng Chen, Yue-Fang Ye, Kui-Fen Ma, Shao-Hua Chen, Lin Zheng, Yi-Da Yang and Xi Jin
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81000169 National Natural Science Foundation of China 81100277 National Natural Science Foundation of China 81200284 Excellent Young Investigator Foundation of Health Bureau of Zhejiang Province, China 2010QNA011 Excellent Young Investigator Natural Science Foundation of Zhejiang Province, China Project R2110159 Project of Zhejiang Traditional Chinese Medicine Administration Bureau Project 2010ZA065 National Technology Supporting Project 2008BAI52B03
Corresponding Author	Xi Jin, MD, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. jxfl007@hotmail.com
Key Words	Crohn's disease; Helicobacter pylori; Urea breath test; Biopsy; Pathogenesis; Inflammatory bowel disease; Bacteria
Core Tip	The association between Helicobacter pylori (H. pylori) infection and Crohn's disease (CD) prevalence is still unclear. In this retrospective study, we collected 229 CD patients and 248 control subjects to investigate the risk factors for prevalence, extent and severity of CD. Through extensive analysis, we found significantly lower H. pylori infection rates in CD patients having different disease extent and severity, providing evidence for bacteria involvement in CD pathogenesis and serving as a reminder for clinicians to remain cautious when considering H. pylori eradication in CD patients.
Publish Date	2013-07-29 11:18
Citation	Xiang Z, Chen YP, Ye YF, Ma KF, Chen SH, Zheng L, Yang YD, Jin X. Helicobacter pylori and Crohn’s disease: A retrospective single-center study from China. World J Gastroenterol 2013; 19(28): 4576-4581
URL	http://www.wjgnet.com/1007-9327/full/v19/i28/4576.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i28.4576

Full Article (PDF)	WJG-19-4576.pdf
Manuscript File	1232-Review.docx
Answering Reviewers	1232-Answering reviewers.pdf
Copyright License Agreement	1232-Copyright assignment.docx
Non-Native Speakers of English Editing Certificate	1232-Language certificate.pdf
Peer-review Report	1232-Peer review(s).pdf
Scientific Editor Work List	1232-Scientific editor work list.doc