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10/22/2026 2:34:08 AM | Browse: 1 | Download: 8
Publication Name World Journal of Clinical Oncology
Manuscript ID 123273
Country China
Received
2026-05-14 07:57
Peer-Review Started
2026-05-14 07:57
First Decision by Editorial Office Director
Return for Revision
2026-07-02 01:34
Revised
2026-07-15 06:29
Publication Fee Transferred
2026-08-15 16:34
Second Decision by Editor
2026-09-24 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-24 08:43
Articles in Press
2026-09-24 08:43
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-15 01:42
Publish the Manuscript Online
2026-10-22 02:34
ISSN 2218-4333 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Obstetrics & Gynecology
Manuscript Type Meta-Analysis
Article Title Endometrial polypoid adenomyoma outcomes and fertility-sparing treatments efficacy for atypical type: A systematic review and network meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Jie-Zhuang Huang, Xia Liu, Ya-Wen Deng, Cai-Ni Wei, Shu-Li Tang and Zhi-Fu Zhi
ORCID
Author(s) ORCID Number
Jie-Zhuang Huang http://orcid.org/0009-0006-8471-3826
Zhi-Fu Zhi http://orcid.org/0000-0001-5846-5415
Funding Agency and Grant Number
Corresponding Author Zhi-Fu Zhi, Department of Gynecology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. zhizhifu525@163.com
Key Words Atypical polypoid adenomyoma; Typical polypoid adenomyoma; Fertility-sparing management; Hysteroscopy; Progestin-based treatment
Core Tip Atypical polypoid adenomyoma (APA) carries a significantly higher risk of concurrent endometrial hyperplasia and cancer than typical polypoid adenomyoma. In this first network meta-analysis comparing fertility-sparing treatments for APA, transcervical resection of polyps (TCRP) followed by medroxyprogesterone acetate (10 mg/day) proved most effective for achieving complete response and preventing recurrence. Additionally, TCRP with subsequent high-dose progestin was most effective for preventing cancer progression. These findings provide critical evidence-based guidance for managing APA in reproductive-aged women.
Publish Date 2026-10-22 02:34
Citation

Huang JZ, Liu X, Deng YW, Wei CN, Tang SL, Zhi ZF. Endometrial polypoid adenomyoma outcomes and fertility-sparing treatments efficacy for atypical type: A systematic review and network meta-analysis. World J Clin Oncol 2026; 17(10): 123273

URL https://www.wjgnet.com/2218-4333/full/v17/i10/123273.htm
DOI https://doi.org/10.5306/wjco.123273
Full Article (PDF) WJCO-17-123273-with-cover.pdf
PRISMA 2009 Checklist 123273-PRISMA-2009-Checklist.pdf
Manuscript File 123273_Auto_Edited_022220.docx
Answering Reviewers 123273-answering-reviewers.pdf
Audio Core Tip 123273-audio.mp3
Biostatistics Review Certificate 123273-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 123273-conflict-of-interest-statement.pdf
Copyright License Agreement 123273-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 123273-non-native-speakers.pdf
Supplementary Material 123273-supplementary-material.pdf
Peer-review Report 123273-peer-reviews.pdf
Scientific Misconduct Check 123273-scientific-misconduct-check.png
CrossCheck Report 123273-crosscheck-report.pdf