| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Prevalence and risk factors for metabolic dysfunction-associated steatotic liver disease and fibrosis in recently diagnosed type 2 diabetes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Astrid Ruiz-Margáin, Oscar Manuel Fierro-Angulo, Jose Alberto Gonzalez-Regueiro, Sergio Cesar Hernández-Jiménez, Ana Cristina García-Ulloa, Victoria Landa-Anell, Fernando Bril, Berenice Montserrat Roman-Calleja, Regina Romo-Arellano, Ariana Pereira-García, Naga Chalasani and Ricardo Ulises Macías-Rodríguez |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Ricardo Ulises Macías-Rodríguez, Associate Professor, MD, PhD, Research Assistant Professor, Division of Hepatology and Liver Transplant, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ), Av. Vasco de Quiroga 15, Col. Belisario Dominguez Secc. XVI, Mexico 14080, Ciudad de México, Mexico. ricardo.maciasr@incmnsz.mx |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Type 2 diabetes mellitus; Steatotic liver disease; Liver fibrosis |
| Core Tip |
There is scarce data specifically evaluating the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and liver fibrosis in patients with recent-onset type 2 diabetes (< 5 years since diagnosis) and without micro or macrovascular complications. The Hispanic population is regarded as high-risk for metabolic diseases, including MASLD. We found a high prevalence of MASLD, affecting 41.4% of the study population, with 10% presenting clinically significant liver fibrosis (liver stiffness measurement ≥ 8 kPa) and 3% having cirrhosis. Our findings support incorporating liver health screening into the routine evaluation of patients with type 2 diabetes mellitus from diagnosis, even in those with good glycemic control and without chronic complications. |
| Publish Date |
2026-08-18 03:51 |
| Citation |
Ruiz-Margáin A, Fierro-Angulo OM, Gonzalez-Regueiro JA, Hernández-Jiménez SC, García-Ulloa AC, Landa-Anell V, Bril F, Roman-Calleja BM, Romo-Arellano R, Pereira-García A, Chalasani N, Macías-Rodríguez RU. Prevalence and risk factors for metabolic dysfunction-associated steatotic liver disease and fibrosis in recently diagnosed type 2 diabetes. World J Hepatol 2026; 18(8): 123278
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i8/123278.htm |
| DOI |
https://doi.org/10.4254/wjh.123278 |
