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7/21/2026 7:21:41 AM | Browse: 3 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 123291
Country China
Received
2026-05-14 07:28
Peer-Review Started
2026-05-14 07:28
First Decision by Editorial Office Director
2026-05-19 02:08
Return for Revision
2026-05-19 02:08
Revised
2026-06-03 06:16
Publication Fee Transferred
2026-06-04 12:03
Second Decision by Editor
2026-06-26 02:16
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-26 07:42
Articles in Press
2026-06-26 07:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-15 09:40
Publish the Manuscript Online
2026-07-21 07:21
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Case Report
Article Title Fish oil emulsion for reversal of intestinal failure-associated liver disease in preterm infants: Three case reports and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Hong-Ju Chen, Zhuo-Ga Danzeng, Peng-Fei Ye, Xiao-Ming Xu, Juan Liang and Li Zhang
ORCID
Author(s) ORCID Number
Hong-Ju Chen http://orcid.org/0000-0002-9391-536X
Peng-Fei Ye http://orcid.org/0000-0003-2790-124X
Juan Liang http://orcid.org/0000-0002-6640-373X
Li Zhang http://orcid.org/0000-0001-5233-5708
Funding Agency and Grant Number
Funding Agency Grant Number
Clinical research funding of West China Second University Hospital, Sichuan University KL073
National Natural Science Foundation of China (General Program) 81501304
Corresponding Author Juan Liang, Department of Pediatrics, West China Second University Hospital, Sichuan University, No. 20 Section 3, Renmin South Road, Wuhou District, Chengdu 610041, Sichuan Province, China. liangjuan079@163.com
Key Words Intestinal failure-associated liver disease; Fish oil lipid emulsion; Parenteral nutrition; Preterm infants; Case report
Core Tip Prolonged parenteral nutrition in preterm infants can lead to intestinal failure-associated liver disease (IFALD). We describe three preterm infants with severe IFALD who were treated with pure fish oil lipid emulsion (FO-ILE) at 2 g/kg/day—higher than conventional protocols. This approach was associated with a rapid decline in direct bilirubin levels and was well tolerated without evidence of essential fatty acid deficiency, growth impairment, or bleeding complications. To the best of our knowledge, this report is among the first reports of high-dose FO-ILE for severe IFALD in preterm infants, a vulnerable population because of hepatic immaturity.
Publish Date 2026-07-21 07:21
Citation

Chen HJ, Danzeng ZG, Ye PF, Xu XM, Liang J, Zhang L. Fish oil emulsion for reversal of intestinal failure-associated liver disease in preterm infants: Three case reports and review of literature. World J Clin Cases 2026; 14(21): 123291

URL https://www.wjgnet.com/2307-8960/full/v14/i21/123291.htm
DOI https://doi.org/10.12998/wjcc.123291
Full Article (PDF) WJCC-14-123291-with-cover.pdf
CARE Checklist–2016 123291-CARE-Checklist-2016.pdf
Manuscript File 123291_Auto_Edited_073107.docx
Answering Reviewers 123291-answering-reviewers.pdf
Audio Core Tip 123291-audio.mp3
Conflict-of-Interest Disclosure Form 123291-conflict-of-interest-statement.pdf
Copyright License Agreement 123291-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 123291-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 123291-non-native-speakers.pdf
Peer-review Report 123291-peer-reviews.pdf
Scientific Misconduct Check 123291-scientific-misconduct-check.png
Scientific Editor Work List 123291-scientific-editor-work-list.pdf
CrossCheck Report 123291-crosscheck-report.pdf