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8/24/2026 9:20:55 AM | Browse: 1 | Download: 0
Publication Name World Journal of Clinical Oncology
Manuscript ID 123351
Country China
Received
2026-05-18 07:41
Peer-Review Started
2026-05-18 07:42
First Decision by Editorial Office Director
Return for Revision
2026-07-13 03:27
Revised
2026-07-27 03:10
Publication Fee Transferred
2026-08-14 08:04
Second Decision by Editor
2026-08-20 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-20 08:42
Articles in Press
2026-08-20 08:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-21 02:01
Publish the Manuscript Online
2026-08-24 09:20
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Xing Wu, Hou-Dun Yang, Jiang Min, Chao Yuan, Lian-Shuo Li, Wei Zhang and Yue Tong
ORCID
Author(s) ORCID Number
Wei Zhang http://orcid.org/0000-0002-5822-9970
Yue Tong http://orcid.org/0009-0007-6412-6509
Funding Agency and Grant Number
Funding Agency Grant Number
Chongqing Municipal Science and Technology Bureau CSTB2025NSCQ-GPX1134
Corresponding Author Yue Tong, Academic Fellow, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. natual101@gmail.com
Key Words Borrmann type IV; Gastric cancer; Intra-arterial chemoembolization; Gastrectomy; Lymph node
Core Tip Borrmann type IV gastric cancer has a poor prognosis because of its diffuse and infiltrative growth pattern. In this retrospective cohort of 70 patients, neoadjuvant intra-arterial chemoembolization followed by gastrectomy achieved an objective response rate of 40.0% with manageable toxicity. Primary-tumor pathological response was associated with better survival in unadjusted analyses, whereas N-stage regression remained independently associated with improved overall survival and disease-free survival after multivariable adjustment. Postoperative complications were associated with worse outcomes. These findings support N-stage regression as a clinically relevant prognostic marker and warrant prospective evaluation of intra-arterial chemoembolization as a therapeutic strategy for Borrmann type IV gastric cancer.
Publish Date 2026-08-24 09:20
Citation

Wu XX, Yang HD, Min J, Yuan C, Li LS, Zhang W, Tong Y. Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer. World J Clin Oncol 2026; 17(8): 123351

URL https://www.wjgnet.com/2218-4333/full/v17/i8/123351.htm
DOI https://doi.org/10.5306/wjco.123351
Full Article (PDF) WJCO-17-123351-with-cover.pdf
Manuscript File 123351_Auto_Edited_020403.docx
Answering Reviewers 123351-answering-reviewers.pdf
Audio Core Tip 123351-audio.mp3
Biostatistics Review Certificate 123351-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 123351-conflict-of-interest-statement.pdf
Copyright License Agreement 123351-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 123351-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 123351-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 123351-non-native-speakers.pdf
Supplementary Material 123351-supplementary-material.pdf
Peer-review Report 123351-peer-reviews.pdf
Scientific Misconduct Check 123351-scientific-misconduct-check.png
CrossCheck Report 123351-crosscheck-report.pdf