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10/21/2026 2:09:41 AM | Browse: 1 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 123353
Country Thailand
Received
2026-05-18 09:31
Peer-Review Started
2026-05-18 09:31
First Decision by Editorial Office Director
Return for Revision
2026-07-05 09:04
Revised
2026-07-17 08:55
Publication Fee Transferred
2026-08-06 02:05
Second Decision by Editor
2026-09-14 03:05
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-15 09:27
Articles in Press
2026-09-15 09:27
Edit the Manuscript by Language Editor
2026-09-17 09:19
Typeset the Manuscript
2026-10-12 01:24
Publish the Manuscript Online
2026-10-21 02:09
ISSN 1948-5182 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Translational Research
Article Title Cost-utility analysis of glucagon-like peptide-1 receptor agonists for type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease in Thailand
Manuscript Source Unsolicited Manuscript
All Author List Sirada Limwongse, Paninnuch Chatpattanasiri, Phonnaphat Phuphuang, Krisada Tungthaweethong, Keerati Sutheerayongprasert, Watkornphat Aunprom-Me, Chayanis Kositamongkol and Pochamana Phisalprapa
ORCID
Author(s) ORCID Number
Sirada Limwongse http://orcid.org/0009-0001-2380-9836
Paninnuch Chatpattanasiri http://orcid.org/0009-0006-9447-1349
Phonnaphat Phuphuang http://orcid.org/0009-0008-2201-7870
Krisada Tungthaweethong http://orcid.org/0009-0007-3303-795X
Keerati Sutheerayongprasert http://orcid.org/0009-0005-2656-1927
Watkornphat Aunprom-Me http://orcid.org/0009-0006-0383-6526
Chayanis Kositamongkol http://orcid.org/0000-0001-7182-0733
Pochamana Phisalprapa http://orcid.org/0000-0003-1995-4405
Funding Agency and Grant Number
Corresponding Author Pochamana Phisalprapa, Associate Professor, Lecturer, MD, PhD, Senior Researcher, Division of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, No. 2 Wanglang Road, Siriraj, Bangkok Noi, Bangkok 10700, Thailand. pochamana.phi@mahidol.ac.th
Key Words Cost-utility analysis; Diabetes mellitus; Glucagon-like peptide-1 receptor agonists; Metabolic dysfunction-associated steatotic liver disease; Thailand
Core Tip This cost-utility analysis evaluated semaglutide and liraglutide for adults with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease in Thailand. Using a lifetime Markov model, we found that the incremental cost-effectiveness ratios of both drugs, relative to usual care, exceeded the national willingness-to-pay threshold. Neither drug was therefore cost-effective. Achieving cost-effectiveness would require price reductions exceeding 90%. These findings underscore the urgent need for drug price negotiations to improve treatment access within Thailand’s healthcare system.
Publish Date 2026-10-21 02:09
Citation

Limwongse S, Chatpattanasiri P, Phuphuang P, Tungthaweethong K, Sutheerayongprasert K, Aunprom-Me W, Kositamongkol C, Phisalprapa P. Cost-utility analysis of glucagon-like peptide-1 receptor agonists for type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease in Thailand. World J Hepatol 2026; 18(10): 123353

URL https://www.wjgnet.com/1948-5182/full/v18/i10/123353.htm
DOI https://doi.org/10.4254/wjh.123353
Full Article (PDF) WJH-18-123353-with-cover.pdf
Manuscript File 123353_Auto_Edited_020319.docx
Answering Reviewers 123353-answering-reviewers.pdf
Audio Core Tip 123353-audio.mp3
Biostatistics Review Certificate 123353-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 123353-conflict-of-interest-statement.pdf
Copyright License Agreement 123353-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 123353-informed-consent-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 123353-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 123353-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 123353-non-native-speakers.pdf
Supplementary Material 123353-supplementary-material.pdf
Peer-review Report 123353-peer-reviews.pdf
Scientific Misconduct Check 123353-scientific-misconduct-check.png
CrossCheck Report 123353-crosscheck-report.pdf