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7/29/2026 2:24:20 AM | Browse: 1 | Download: 0
Publication Name World Journal of Translational Medicine
Manuscript ID 123433
Country China
Received
2026-05-19 07:40
Peer-Review Started
2026-05-19 07:40
First Decision by Editorial Office Director
Return for Revision
2026-06-17 14:19
Revised
2026-06-27 05:52
Publication Fee Transferred
Second Decision by Editor
2026-07-02 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-02 08:17
Articles in Press
2026-07-02 08:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-08 01:42
Publish the Manuscript Online
2026-07-29 02:24
ISSN 2220-6132 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Risk factors for pathological upgrading pre- and post-endoscopic resection of colorectal adenoma: A retrospective study
Manuscript Source Invited Manuscript
All Author List Xu-Lin Zheng, Tao Chen, Yang Yu, Neng Wang, Biao Jiang, Yao Yao, Yun-Fei Zhao, Xin-Xin Yu and Chun-Lin Su
ORCID
Author(s) ORCID Number
Xu-Lin Zheng http://orcid.org/0000-0002-2169-1950
Tao Chen http://orcid.org/0000-0002-2707-0274
Xin-Xin Yu http://orcid.org/0009-0004-1786-2050
Chun-Lin Su http://orcid.org/0009-0009-0187-2584
Funding Agency and Grant Number
Funding Agency Grant Number
the Joint Growth Program for Early Gastrointestinal Cancer Physicians of China, Beijing Huaxia Cancer Prevention and Research Institute Grant No. GTCZ-2024-09
Corresponding Author Chun-Lin Su, Department of Gastroenterology, Gastrointestinal Endoscopy Center, Suining Central Hospital, No.127 Desheng West Road, Chuanshan District, Suining 629000, Sichuan Province, China. 13408251310@163.com
Key Words Colorectal adenoma; Colorectal cancer; Pathological upgrading; Endoscopic resection; Risk factor; Retrospective study
Core Tip Colorectal adenomas (CRAs) are the predominant precancerous lesions of colorectal cancer. Assessing their pathological upgrading risk is critical for early diagnosis and intervention. In this retrospective study, pathological upgrading incidence was significantly higher in adenomas with a diameter > 20 mm than in those ≤ 20 mm. Adenoma diameter was an independent influencing factor for the pathological upgrading of CRAs. CRAs with a diameter > 20 mm are more susceptible to pathological upgrading and carry an elevated risk of undetected high-grade dysplasia or early carcinoma missed by preoperative biopsy. Early and complete endoscopic resection is recommended to prevent progression to colorectal cancer. These findings will enhance clinicians’ diagnostic capabilities and assist in formulating appropriate treatment strategies for CRAs.
Publish Date 2026-07-29 02:24
Citation

Zheng XL, Chen T, Yu Y, Wang N, Jiang B, Yao Y, Zhao YF, Yu XX, Su CL. Risk factors for pathological upgrading pre- and post-endoscopic resection of colorectal adenoma: A retrospective study. World J Transl Med 2026; 12(2): 123433

URL https://www.wjgnet.com/2220-6132/full/v12/i2/123433.htm
DOI https://doi.org/10.5528/wjtm.123433
Full Article (PDF) WJTM-12-123433-with-cover.pdf
Manuscript File 123433_Auto_Edited_022402.docx
Answering Reviewers 123433-answering-reviewers.pdf
Audio Core Tip 123433-audio.mp3
Biostatistics Review Certificate 123433-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 123433-conflict-of-interest-statement.pdf
Copyright License Agreement 123433-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 123433-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 123433-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 123433-non-native-speakers.pdf
Peer-review Report 123433-peer-reviews.pdf
Scientific Misconduct Check 123433-scientific-misconduct-check.png
Scientific Editor Work List 123433-scientific-editor-work-list.pdf